Please use this identifier to cite or link to this item: http://hdl.handle.net/10201/19055

Title: Distribution of VIP receptors in the human submandibular gland, an immunohistochemical study
Issue Date: 1998
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::6 - Ciencias aplicadas::61 - Medicina
Keywords: Submandibular gland
Immunohistochemistry
Abstract: Distribution of vasoactive intestinal polypeptide (VIP)-immunoreactive nerve fibers and VIPreceptor (VIP-R)-immunoreactive sites in the human submandibular gland were examined by the peroxidaseantiperoxidase method using the specimens taken from patients that had not received radiotherapy. VIP-immunoreactive fibers were found around both serous and mucous acini, the duct system, and those around the mucous acini were more numerous than those around the serous acini. VIP-R immunoreactivity was restricted to the mucous acini and the intercalated duct segment. The serous acini, striated duct, and excretory ducts lacked VIP-R immunoreactivity. These findings suggest that the mucous acinar cells contain VIP-R, and that VIP-R-mediated VIP action is involved in regulating synthesis of viscous saliva and its release.
Primary author: Kusakabe, T.
Matsuda, H.
Gono, Y.
Kawakami, T.
Kurihara, K.
Tsukuda, M.
Takenaka, T.
Published in: Histology and histopathology
URI: http://hdl.handle.net/10201/19055
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 6
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol.13, nº 2 (1998)



Items in Digitum are protected by copyright, with all rights reserved, unless otherwise indicated.