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Título: | Diabetic nephropathy, the modulating influence of glucose on transforming factor D production |
Fecha de publicación: | 1998 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Diabetes Pathogenesis |
Resumen: | Diabetes in now the commonest cause of renal failure in the western world. Furthermore the survival of diabetic patients requiring dialysis treatment for renal failure is far less than patients with renal failure secondary to all other diseases. It is therefore important to identify the factors that control the development of progressive renal disease to allow targeted therapeutic interventions which would have major implications both to patient well-being and also to the provision of health care world wide. In this review we discuss possible metabolic consequences of hyperglycemia and their role in the pathogenesis of diabetic nephropathy. We also focus on the involvement of the pro-fibrotic cytokine Transforming Growth Factor B, and contrast its role in the pathogenesis of glomerular and tubulo-interstitial changes seen in diabetic nephropathy. |
Autor/es principal/es: | Phillips, A.O. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/19049 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 10 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.13, nº 2 (1998) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Diabetic nephropathy the modulating influence of glucose on transforming factor D production.pdf | 7,72 MB | Adobe PDF | Visualizar/Abrir |
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