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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Imai, Yutaka | es |
dc.contributor.author | Yamakawa, Mitsunori | es |
dc.contributor.author | Kasajima, Takeshi | - |
dc.date.accessioned | 2011-02-22T10:58:22Z | - |
dc.date.available | 2011-02-22T10:58:22Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/19047 | - |
dc.description.abstract | Antigens provoke immune responses. The group of immunocompetent cells related directly to this response includes T and B cells, macrophages (MO) and dendritic cells (DCs). DCs acting as antigen-presenting cells have been recently recognized to be important in initiating the immune response. B cells and follicular dendritic cells (FDCs), the major immunocompetent cells in the B-cell dependent area, play an important role in humoral immunity, while T cells and interdigitating cells (IDCs), which are the major immunocompetent cells in the T-cell dependent (TD)-area, play an important role in cellular immunity. The B cell-IDC interaction in the TD-area is also essential for the B-cell response against TD-antigen. Consequently, the lymphocyte-DC interaction is essential in the response to antigenic stimulation and in inducing the potent effector cells. B cell-DC, T cell-DC and DC-B cell-T cell interactions are regulated in predetermined sites by complex and varied mechanisms. Much recent evidence demonstrates that DCs modulate lymphocyte biology in its broadest aspects, including generation, differen-tiation, proliferation, and activation. In this review, we outline recent studies on the generation, structure, and function of lymphatic tissues, propose the concept of the "Lymphocyte-Dendritic Cell System (LDS)", and finally describe the significance and functions of this system in health and disease. | es |
dc.format | application/pdf | es |
dc.format.extent | 42 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Lymphoid follicle | es |
dc.subject | Germinal centre | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina | es |
dc.title | The lymphocyte-dendritic cell system | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.13, nº 2 (1998) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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The lymphocytedendritic cell system.pdf | 994,28 kB | Adobe PDF | Visualizar/Abrir |
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