Please use this identifier to cite or link to this item: http://hdl.handle.net/10201/18997

Full metadata record
DC FieldValueLanguage
dc.contributor.authorChidgey, M.A.J.es
dc.date.accessioned2011-02-22T10:42:23Z-
dc.date.available2011-02-22T10:42:23Z-
dc.date.issued1997-
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18997-
dc.description.abstractConsiderable progress has been made in our knowledge of desmosomes and their components. Molecular cloning of the desmosomal glycoproteins has established that desmoglein 1 and desmoglein 3 are targets for autoantibodies in the blistering diseases pemphigus foliaceus and pemphigus vulgaris respectively. New evidence suggests that another desmosomal glycoprotein, desmocollin 1, is the major target antigen in the upper epidermal form of intercellular IgA dermatosis (IgA pemphigus). In human cancer there is accumulating evidence which suggests a role for desmosomes in the prevention of invasion and metastasis. The possibility exists that a mutation in a desmosomal glycoprotein gene is responsible for an inheritable human disease, the striated form of palmoplantar keratodenna.es
dc.formatapplication/pdfes
dc.format.extent10es
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectDesmosomees
dc.subjectCanceres
dc.subject.otherCDU::5 - Ciencias puras y naturales::57 - Biologíaes
dc.titleDesmosomes and diseasees
dc.typeinfo:eu-repo/semantics/articlees
Appears in Collections:Vol.12, nº 4 (1997)

Files in This Item:
File Description SizeFormat 
Desmosomes and disease.pdf6,4 MBAdobe PDFThumbnail
View/Open


Items in Digitum are protected by copyright, with all rights reserved, unless otherwise indicated.