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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Nicòtina, P.A. | es |
dc.contributor.author | Ferlazzo, G. | es |
dc.contributor.author | Vincelli, A.M. | - |
dc.date.accessioned | 2011-02-22T10:42:20Z | - |
dc.date.available | 2011-02-22T10:42:20Z | - |
dc.date.issued | 1997 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/18994 | - |
dc.description.abstract | Mixed mullerian tumor (MMT) is a biphasic malignancy of elderly women. It, including both a carcinomatous and a sarcomatous component (CC and SC), is regarded as a female genital tract carcinosarcoma (FGTCS). Since current methods to grade CC and SC are not still univocal, the authors estimate mitotic index (MI) and MIB 1-immunolabeling index (MIB 1-LI) as common prognostic indices for the MMT components. They also compare above prognostic indices with p-53 immunocytochernistry, in MMTs. The present study thus points out that: (a) MI of CC and SC areas is consistent with the respective conventional tumor grades; (b) MI averages of CC are higher than those observed in the SC areas; (c) MI and MIB 1-LI of the CC-tumor cells correlate reciprocally in a very significant fashion; (d) A diffuse strong p53 nuclear immunostaining (SO% cells) is often patent where the highest MI and MIB 1-LI are found. In conclusion, the authors propose MI and MIB 1-LI as two complementary useful indices to assess prognosis of MMTs. They also suggest p53 nuclear immunolabeling should be regarded as an independent biomarker of unfavourable MMT behaviour. | es |
dc.format | application/pdf | es |
dc.format.extent | 6 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Proliferation indices | es |
dc.subject | Mitotic index | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología | es |
dc.title | Proliferation indices and p53-immunocytochemistry in uterine mixed mullerian tumors | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.12, nº 4 (1997) |
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Fichero | Descripción | Tamaño | Formato | |
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Proliferation indices and p53immunocytochemistry.pdf | 3,57 MB | Adobe PDF | Visualizar/Abrir |
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