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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Pettit, E.J. | es |
dc.contributor.author | Davies, E.V. | es |
dc.contributor.author | Hallett, M.B. | - |
dc.date.accessioned | 2011-02-22T10:41:02Z | - |
dc.date.available | 2011-02-22T10:41:02Z | - |
dc.date.issued | 1997 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/18935 | - |
dc.description.abstract | As changes in cytosoiic free ca2+ play key roles in coupling responses in neutrophils, it is important to locate and identify ca2+ storage sites within these cells. Here, recent data is presented which highlights the functional link between rnicroanatomical structure and cell signailing function. Fluorescent opticai probes for cytosolic free ca2+ have been used, together with organelle specific markers. We present evidence from conventional fluorescence microscopy, together with ratiometric and confocal laser scanning fluorescence microscopy, which pin-points two celiular locations for ca2+ within the neutrophil; one within the nuclear lobes, and the other towards the ceii periphery. Knowledge of these two locations provides a clear insight into how signailing in this cell type is regulated and provides a framework for explaining how specific stimuli act to produce specific responses. | es |
dc.format | application/pdf | es |
dc.format.extent | 12 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Neutrophils | es |
dc.subject | Calcium stores | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina | es |
dc.title | The microanatomy of calcium stores in human neutrophils, Relationship of structure to function | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.12, nº 2 (1997) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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The microanatomy of calcium stores in human neutrophils Relationship of structure to function.pdf | 7,73 MB | Adobe PDF | Visualizar/Abrir |
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