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Título: | Morphometric evidence of the regulation of the activity of LH-immunoreactive cells by corticosterone. An in vivo and in vitro study |
Fecha de publicación: | 1996 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía |
Palabras clave: | Corticosterone Adrenalectomy |
Resumen: | The present study was performed to investigate the morphometric effects of the administration of corticosterone on LH-immunoreactive cells of pituitary monolayer cultures. In addition, the effect of bilateral adrenalectomy on the LH-adenohypophyseal cells was explored. In vitro administration of corticosterone induced a marked decrease in the morphometric parameters considered (cellular, cytoplasmic and nuclear areas). In vivo, bilateral adrenalectomy produced a significant increase in these parameters when compared to those obtained in normal and sham-operated animals. However, when the bilaterally adrenalectomized rats received a daily dose of corticosterone no significant changes in the morphometric parameters were found. Morphometrically, these combined in vivo-in vitro findings confirm a corticosterone-induced hypoactivity of LI4-cells together with a direct effect of this glucocorticoid on LH-adenohypophyseal cells. |
Autor/es principal/es: | Rubio, M. Carretero, J. Cabo, J.J. Santos, M. Vázquez, R.J. Vázquez, R. Sánchez, F. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18895 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 5 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.11, nº 4 (1996) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Morphometric evidence of the regulation of the activity of LHimmunoreactive cells by corticosterone. An in vivo and in vitro study.pdf | 2,77 MB | Adobe PDF | Visualizar/Abrir |
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