Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10201/18526

Registro completo de metadatos
Campo DCValorLengua/Idioma
dc.contributor.authorMarkowska, A.es_ES
dc.contributor.authorNussdorfer, G.G.es_ES
dc.contributor.authorMalendowicz, L.K.-
dc.date.accessioned2011-02-01T09:18:26Z-
dc.date.available2011-02-01T09:18:26Z-
dc.date.issued1994-
dc.identifier.issn0213-3911es_ES
dc.identifier.urihttp://hdl.handle.net/10201/18526-
dc.description.abstractEvidence indicates that neurotensin (NT) and neuromedin-N (NMN) exerts an adrenocorticotropic effect in the rat. The present study aimed to investigate whether these neuropeptides are able to stimulate the proliferation of rat adrenocortical cells in vivo and to compare their mode of action. Adrenocortical proliferative activity was assessed by the metaphasearrest technique and metaphases were counted per medulla-containing adrenal section. A bolus administration of NT (3 pglrat) resulted in a significant increase in the number of metaphases in both zona fasciculata and the entire cortex, an effect observed 48 h after the in.jection. The administration of NMN (3 yglrat) induced a notable rise in the number of metaphases in the zona fasciculata and the entire cortex within 12 h, followed by a subsequent drop after 24 h and a return to normal values at 48 h. These findings indicate that NT and NMN enhance rat adrenal growth in vivo acting via different mediators.es_ES
dc.formatapplication/pdfes_ES
dc.format.extent4es_ES
dc.languageenges_ES
dc.publisherMurcia : F. Hernándezes_ES
dc.relation.ispartofHistology and histopathologyes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectNeurotensines_ES
dc.subjectNeuromedin Nes_ES
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes_ES
dc.titleDifferent effects of neurotensin and neuromedin-N on the proliferative activity of rat adrenal cortexes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
Aparece en las colecciones:Vol. 9, nº 3 (1994)

Ficheros en este ítem:
Fichero Descripción TamañoFormato 
Different effects of neurotensin and neuromedinN on the proliferative activity of rat adrenal cortex.pdf188,05 kBAdobe PDFVista previa
Visualizar/Abrir


Los ítems de Digitum están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.