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Título: Effect of dietary fat on toad liver tumor induced by DMBA. Ultrastructural studies
Fecha de publicación: 1994
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina
Palabras clave: DMBA
Toads
Resumen: Toads injected with 2 mg 7,12-dimethylbenza( a)anthracene (DMBA)/toad, 3 timeslweek for 12 weeks induced liver tumors in 12 out of 50 cases. The electron micrograph of toad liver tumor showed disorganization of the rough endoplasmic reticulum which encircles or partially surrounds the mitochondria. Cristae mitochondrialis are rare in comparison with control. Enhancement of liver tumor incidences (29 out of 50 cases) by DMBA at the same dose level plus 2cc corn oilltoad, 3 timeslweek for 12 weeks was detected. Electronmicrograph of this group showed the same criteria of malignancy as in the first group. No tumor incidences were detected in toads fed corn oil only. The electronmicrograph of liver cells showed a high increase in glycogen and lipid droplets.
Autor/es principal/es: Sadek, I.A.
Abdul-Salarn, F.
Publicado en: Histology and histopathology
URI: http://hdl.handle.net/10201/18520
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 4
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol. 9, nº 3 (1994)

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