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dc.contributor.authorCsanaky, G.es_ES
dc.date.accessioned2011-02-01T09:18:12Z-
dc.date.available2011-02-01T09:18:12Z-
dc.date.issued1994-
dc.identifier.issn0213-3911es_ES
dc.identifier.urihttp://hdl.handle.net/10201/18508-
dc.description.abstractThe high endothelial venule (HEV)-content and the lymphocyte migration index (LMI) of reactive lymph nodes and lymph nodes from patients with B-cell chronic lymphocytic leukaemia (B-CLL), as well as some related B-cell malignancies (lymphocytic lymphoma -LL-, prolymphocytic leukaemia -PLL-) were determined and statistically analyzed. The HEV-content and the LMI were significantly higher in reactive lymph nodes than in the low grade B-cell lymphomas and leukaemias (p< 0.001). The number of HEVs among lymphoma/leukaemia cases was the highest in LL independently of the maturation. However, the maturation of the process seems to determine the intensity of lymphocyte migration; i.e. a significantly higher LMI was found in mature (B-CLL, PF, mature; M and LL, M) than in immature subtypes (B-CLL, PF, immature -1M-, diffuse -D- and LL, IM) subtypes (levels of significance varied from p< 0.05 to p< 0.001). Rased on these findings, a more intense migration of lymphocytes from blood to peripheral lymph nodes may be supposed in LL than in B-CLL, thus explaining the nodal sites of involvement in LL and the peripheral blood in B-CLL. Within the same histological categories the morphometric features in mature subtypes may implicate an enhanced HEV-lymphocyte interaction when compared to the immature subtypes.es_ES
dc.formatapplication/pdfes_ES
dc.format.extent5es_ES
dc.languageenges_ES
dc.publisherMurcia : F. Hernándezes_ES
dc.relation.ispartofHistology and histopathologyes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectLymphocyte migrationes_ES
dc.subjectDisseminationes_ES
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes_ES
dc.titlePáginas de High endothelial venules and cell adhesion molecules in B cell chronic lymphocytic leukaemia and related low grade B-cell ...es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
Aparece en las colecciones:Vol. 9, nº 3 (1994)



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