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Título: | Lectin histochemistry of human meningiomas |
Fecha de publicación: | 1994 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Lectin Meningioma |
Resumen: | The lectins Peanut agglutinin (PNA), Canavalia ensiformis (Con A), Ulex europaeusl (UEAl), Dolichos biflorus (DBA), Triticum vulgaris (WGA) were studied in a series of 36 meningiomas (16 meningotheliomatous-including 3 recurrences, 7 transitional, 4 angiomatous, 2 ((hemangiopericytic~3, papillary-including 1 recurrence, 4 anaplastic-including 3 recurrences. PNA binds to all cases of meningotheliomatous, transitional, papillary and anaplastic meningiomas (including recurrent cases) but the staining is more intense in tumor cells of anaplastic and papillary type. A semiquantitative study showed differences of PNAreactivity in the different subtypes of meningiomas. In meningotheliomatous meningiomas PNA-positivity was encountered in numerous neoplastic cells (50%), whereas papillary and anaplastic subtypes expressed strong cytoplasmic staining of few tumor cells (C 5%). Con A shows the same pattern of reactivity described for PNA, but more weakly. Our results suggest that PNA is a marker of differentiation in meningiomas rather than malignant transformation and can have prognostic relevance. |
Autor/es principal/es: | Marafioti, T. Barresi, G. Batolo, D. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18503 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 6 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 9, nº 3 (1994) |
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Lectin histochemistry of human meningiomas.pdf | 1,47 MB | Adobe PDF | Visualizar/Abrir |
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