Primary papillary psammomatous adenocarcinoma of the umbilicus

Abstract

The histological and ulhrastructural features, as well as the immunoreactivity of one case of uncommon primary papillary and psammomatous adenocarcinoma of the umbilicus are studied in the present work. The observations have been undertaken in a nine-year follow-up, and have included the primitive tumour, two local recidives, and inguinal lymphatic metastasis on two occasions. Papillary structures, numerous psamrnoma bodies, as well as weak and foca1 positive reactions to CEA and cytokeratin were present in al1 the tumours. Since these features and their ultrastnictural characteristics were identical to pnmary papillary serous neoplasias of the peritoneum and ovarium, the hypothesis of an origin in coelomic rernnants is considered.