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Título: | A quantitative description of the insulin-induced ultrastructural changes in newborn rat hepatocytes |
Fecha de publicación: | 1993 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía |
Palabras clave: | Insulin Newborn rat |
Resumen: | The effects of insulin on the ultrastructure of newborn rat hepatocytes were systernatically quantified at satisfactory statistical significance. Insulin prevented the normal postnatal increase in the total volume of lysosomes and the breakdown of glycogen inside these organelles. The lysosomal glycogen-hydrolysing enzyme, acid alpha 1,4 glucosidase was inhibited by the hormone. Insulin also prevented the normal postnatal increase in the total volume of peroxisomes, especially of the crystalloid core-devoid type. The hormone produced an increase in the area of cell membrane, due to the forrnation of many irregular folds of the cell surface. These results constitute good evidence for participation of lysosomes and peroxisomes in the overall glycogen degradation and or gluconeogenesis in the newborn rat hepatocytes. |
Autor/es principal/es: | Maintas, D.B. Kotoulas, Othon B. Kotoulas, Angeliki O. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18408 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 8 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 8, nº 2 (1993) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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A quantitative description of the insulininduced ultrastructural changes in newborn rat hepatocytes.pdf | 1,52 MB | Adobe PDF | Visualizar/Abrir |
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