Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10201/18408

Título: A quantitative description of the insulin-induced ultrastructural changes in newborn rat hepatocytes
Fecha de publicación: 1993
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía
Palabras clave: Insulin
Newborn rat
Resumen: The effects of insulin on the ultrastructure of newborn rat hepatocytes were systernatically quantified at satisfactory statistical significance. Insulin prevented the normal postnatal increase in the total volume of lysosomes and the breakdown of glycogen inside these organelles. The lysosomal glycogen-hydrolysing enzyme, acid alpha 1,4 glucosidase was inhibited by the hormone. Insulin also prevented the normal postnatal increase in the total volume of peroxisomes, especially of the crystalloid core-devoid type. The hormone produced an increase in the area of cell membrane, due to the forrnation of many irregular folds of the cell surface. These results constitute good evidence for participation of lysosomes and peroxisomes in the overall glycogen degradation and or gluconeogenesis in the newborn rat hepatocytes.
Autor/es principal/es: Maintas, D.B.
Kotoulas, Othon B.
Kotoulas, Angeliki O.
Forma parte de: Histology and histopathology
URI: http://hdl.handle.net/10201/18408
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 8
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol. 8, nº 2 (1993)



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