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Title: Ultrastructural study of neuromuscular junction in rectus femoris muscle of streptozotocin-diabetic rats
Issue Date: 1992
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citología
Keywords: Quadriceps muscle
Neuromuscular junction
Abstract: The neuromuscular junctions (NMJ) from rectus femoris muscle in streptozotocin (STZ) -induced diabetic rats were examined by electron microscopy eight weeks after the STZ injection. When compared to controls and vehicle-injected groups, both the axon terminal and the junctional sarcoplasm showed serious alterations including mitochondrial degeneration, presence of myeloid bodies, breakdown of presynaptic membrane and changes in the form of the synaptic vesicles. The results suggest that NMJ can contribute to the pathogenesis of diabetic proximal myopathy.
Primary author: Medina sánchez, M.
Rodríguez Sáchez, C.
Vega Alvarez, J.A.
Menéndez Peláez, A.
Published in: Histology and histopathology
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 4
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol. 7, nº 4 (1992)

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