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Title: Dermal cylindroma. Expression of intermediate filaments, epithelial and neuroectodermal antigens
Issue Date: 1992
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.5 - Piel. Dermatología clínica
Keywords: Apocrine tumors
Abstract: We report on irnmunohistochemical staining pattems in so-called apocrine tumors of skin with special emphasis on the dermal cylindroma. The results were compared with apocrine tubular adenoma, syringocystadenoma papilliferum and the normal eccrine sweat gland. A relationship of dermal cylindroma to the apocrine gland is suggested by expression of lysozyme and alphal-antichymotrypsin. The tumor shares keratin, epithelial membrane antigen (EMA) and EGF-receptor expresssion with eccrine and apocrine glands. The presence of intermingled cells with a coexpression of keratin and vimentin argues for a partial myoepithelialike differentiation. Neuroectodermal antigens are rnissing. Therefore, dermal cylindroma is classified as an adnexal tumor of skin with a variable rate of cells of apocrine secretory, myoepithelial and undifferentiated phenotypes
Primary author: Wollina, Uwe
Rülke, D.
Schaarschmidt, H.
Published in: Histology and histopathology
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 7
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol. 7, nº 4 (1992)

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