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dc.contributor.authorVaquero, J.es
dc.contributor.authorCoca, S.es
dc.contributor.authorMoreno M.-
dc.contributor.authorOya, S.-
dc.contributor.authorArias, A.-
dc.contributor.authorZurita, M.-
dc.contributor.authorMorales, C.-
dc.date.accessioned2011-02-01T08:47:43Z-
dc.date.available2011-02-01T08:47:43Z-
dc.date.issued1992-
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18343-
dc.description.abstractA series of 18 tumors with histological features of oligodendrogliomas, induced in the rat by means of transplacental ethyl-nitrosurea administration were studied for immunohistochemical demonstration of neuronal (synaptophysin and neurofilament protein) and glial (gliofibrillar acidic protein and vimentin) markers. Most of the tumors showed cells with strong positivity to synaptophysin and to a lesser degree, to neurofilament protein, suggesting the neuronal character of these neoplasms. In 10 tumors, cells with strong positivity to vimentin were found, and in three cases, tumoral cells expressed gliofibrillar acidic protein. The observation that ENU-induced oligodendroglial tumors express neuronal and, to a minor degree, glial markers, suggests their interpretation as prirnitive neuroectodermal tumors with clear neuronal differentiation.es
dc.formatapplication/pdfes
dc.format.extent5es
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectOligodendrogliomaes
dc.subjectImmunohistochemistryes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.8 - Neurología. Neuropatología. Sistema nerviosoes
dc.titleExpression of neuronal and glial markers in so-called oligodendrogilial tumors induced by transplacental administration of ethyl-nitrosourea in the rates
dc.typeinfo:eu-repo/semantics/articlees
Aparece en las colecciones:Vol. 7, nº 4 (1992)



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