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| Título: | Effects of omeprazole on the number of immunoreactive gastrin- and somatostatin-cells in the rat gastric mucosa |
| Fecha de publicación: | 1992 |
| Editorial: | Murcia : F. Hernández |
| ISSN: | 0213-3911 |
| Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
| Palabras clave: | Gastric antral mucosa Omeprazole |
| Resumen: | The effects of omeprazole - an inhibitor of gastric acid secretion - on gastrin (G)- and somatostatin (D)-cell density in the gastric antral mucosa epithelium in rats were examined, following a 5-day treatment. It was found that omeprazole increased the density of G-cells, whereas it decreased the density of D-cells. That effect was probably independent of hypergastrinaemia, since it could not be blocked by a simultaneous treatment with proglumide - a gastrin receptor blocker. It is concluded that the observed phenomenon is a direct result of a lower gastric acidity, as a consequence of omeprazole treatment. |
| Autor/es principal/es: | Pawlikowski, M. Karbownik, M. Lewinski, A. Pisarek, Hanna Wajs, E. Szkudlinski, M. |
| Forma parte de: | Histology and histopathology |
| URI: | http://hdl.handle.net/10201/18295 |
| Tipo de documento: | info:eu-repo/semantics/article |
| Número páginas / Extensión: | 4 |
| Derechos: | info:eu-repo/semantics/openAccess |
| Aparece en las colecciones: | Vol. 7, nº 2 (1992) |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| Effects of omeprazole on the number of immunoreactive gastrin and somatostatincells in the rat gastric mucosa.pdf | 700,15 kB | Adobe PDF |  Visualizar/Abrir |
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