Please use this identifier to cite or link to this item: http://hdl.handle.net/10201/18209

Title: Ultrastructural aspects of human nonunion
Issue Date: 1991
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::6 - Ciencias aplicadas::61 - Medicina::617 - Cirugía. Ortopedia. Oftalmología
Keywords: Human nonunion
Ultrastructure
Abstract: A histological study on the tissue of nonunion of tibias of two young patients was performed to evaluate the ability of cells to start the mineralization of the matrix. The observations can be summarized as follows: 1) Tissue vessels often appear occluded by thrombotic material; 2) Fibroblasts and chondrocytes found in the nonunion tissue seemed normal, with a good secretion apparatus; 3) The cell membranes were able to produce matrix vesicles; 4) Matrix vesicles and cell membrane looked positive to ALPase reaction, 5) Hydroxyapatite crystals could be observed in the cell matrix or inside matrix vesicles. It may be concluded that cells populating nonunion tissue are well equipped to induct the mineralization of the matrix, but the absence of a blood supply, enough to bring them a normal calcium amount, is the real reason for the nonunion.
Primary author: Quacci, Daniela
Dell`Orbo, Carlo
Salvi, Massimiliano
Bartolozzi, Pietro
Misasi, Mario
Published in: Histology and histopathology
URI: http://hdl.handle.net/10201/18209
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 7
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol. 6, nº 1 (1991)

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