Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10201/18196

Título: Changes in the number and distribution of Langerhans cells in the hydantoin hyperplasic gingiva as compared with the clinically normal one
Fecha de publicación: 1990
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citología
Palabras clave: Gingiva
Hydantoin
Resumen: A study was made of the number of Langerhan's cells (LCs) per mm2 of section which express the antigens T, and/or HLA-DR in seriated gingival sections of diphenylhydantoine-induced hyperplasia (HG) and clinically normal gingivae (NG). NG showed histological correlation with its macroscopic appearance. In HG the classical histopathological findings were verified, as well as the epithelial maturation irregularities, conducive to the development of epithelial gaps. In the immunostained samples, LCs appear amply distributed in the epithelium in greater numbers than in NG and more branched except in the immature areas, where they mostly express HLA-DR. In HG keratinocytes, HLA-DR' are observed in the basal layer, except in developing epithelial gap zones. The Wilcoxon test for the NG-T6lNG-DR and HG-T,/HGDR was not significant; but the Mann Whitney test for NG-TdHG-T, and NG-DWHG-DR was significant to p < 0.05. It is understood that the increase in LC numbers in HG is a manifestation of their active participation in local immune reactions. The presence of DR+/T,- LCs in the less keratinized areas seems to indicate the relationship of LCs with epithelial proliferation and/or differentiation.
Autor/es principal/es: Ibañez, P.
Sagredo, E.
Pino, A.
Publicado en: Histology and histopathology
URI: http://hdl.handle.net/10201/18196
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 6
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol. 5, nº 4 (1990)



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