Please use this identifier to cite or link to this item: http://hdl.handle.net/10201/18153

Title: The effects of cyclophosphamide on the gonadotrophic cells of the normal rat
Issue Date: 1990
Publisher: Murcia : F. Hernández
ISSN: 0213-3911
Related subjects: CDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomía
Keywords: Gonadotrophic cells
Cyclophosphamide
Abstract: The effects of the administration of cyclophosphamide to male rats at doses of 400 mg/m2 for a period of 5 days and of 200 mg/m2 over two five-day cycles interrupted by a 21-day break reveal differences in the ultrastructural morphology of gonadotrophic cells between treated animals and normal controls. The ultrastructural data obtained coincide with the results obtained from the measurement of serum FSH and LH levels, indicating hypofunction. A significant fall was also recorded in blood testosterone levels. The two types of treatment did not give rise to morphological or functional differences.
Primary author: Poblador, María S.
Rojas, Carmen
Raya, Antonio
Casares, José A.
Aparicio, J.
Lancho Alonso, José Luis
Published in: Histology and histopathology
URI: http://hdl.handle.net/10201/18153
Document type: info:eu-repo/semantics/article
Number of pages / Extensions: 8
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Vol. 5, nº 2 (1990)

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