Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10201/17933

Título: Pituitary growth hormone secretory granules in streptozotocin-induced diabetic rats
Fecha de publicación: 1988
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina
Palabras clave: Anterior pituitary
Diabetes
Resumen: The ultrastructural features of growth hormone (GH) secretory granules were observed by immuno-gold procedure in the anterior pituitary glands of streptozotocin (STZ) - induced diabetic rats. The diabetic state of rats induced by one injection of STZ was severely advanced at 10 months after the injection. The cytoplasmic organella were revealed to be poorly developed in GH-cells of the diabetic rats. The size of immunoreactive GH-granules of 10-months-old diabetic rats was smaller than that of sham-controls. The insulin therapy in the diabetic rats resulted in a considerable improvement in relation to the changes seen in the GHcells, but the therapy did not return the profile of the granule size distribution to that of the control group
Autor/es principal/es: Masataka Shiino
Toshiko Ishibashi
Publicado en: Histology and histopathology
URI: http://hdl.handle.net/10201/17933
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 6
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol. 3, nº 3 (1988)

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