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Título: | An immunocytochemical method for assaying oestrogen receptors in breast cancers. A comparison with the steroid binding assay |
Fecha de publicación: | 1988 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
Palabras clave: | Breast carcinomas Immunocytochemistry |
Resumen: | The presence of oestrogen receptors was studied in 105 human breast carcinomas using monoclonal antibodies (Abbott ER-ICA kit). The oestrogen receptors of neoplastic cells were semiquantitatively measured and correlations were made to receptor values determined by a dextran-coated charcoal (DCC) steroid binding assay and to histological grade. Immunoreactive cells were found in about 213 of the tumours. Usually only a fraction of the cells within each tumour were immunoreactive, and the staining intensity varied among different cells. In general, well differentiated tumours had a greater proportion of immunoreactive cells than poorly differentiated ones. In most cases (651 98) a good agreement was found between the ER-ICA method and the DCC assay. However, in 33 cases discrepancies were demonstrated. |
Autor/es principal/es: | Ottestad, Lars Tveit, Kjell M. Nesland, Jahn M. Dybsjordl, Indrejit Bormer, Ole Hoie, Johan Pihl, Alexander |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/17928 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 6 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 3, nº 3 (1988) |
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Pituitary growth hormone secretory granules in streptozotocininduced diabetic An immunocytochemical method for assayingrats....pdf | 399,57 kB | Adobe PDF | Visualizar/Abrir |
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