Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10201/17928

Título: An immunocytochemical method for assaying oestrogen receptors in breast cancers. A comparison with the steroid binding assay
Fecha de publicación: 1988
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología
Palabras clave: Breast carcinomas
Immunocytochemistry
Resumen: The presence of oestrogen receptors was studied in 105 human breast carcinomas using monoclonal antibodies (Abbott ER-ICA kit). The oestrogen receptors of neoplastic cells were semiquantitatively measured and correlations were made to receptor values determined by a dextran-coated charcoal (DCC) steroid binding assay and to histological grade. Immunoreactive cells were found in about 213 of the tumours. Usually only a fraction of the cells within each tumour were immunoreactive, and the staining intensity varied among different cells. In general, well differentiated tumours had a greater proportion of immunoreactive cells than poorly differentiated ones. In most cases (651 98) a good agreement was found between the ER-ICA method and the DCC assay. However, in 33 cases discrepancies were demonstrated.
Autor/es principal/es: Ottestad, Lars
Tveit, Kjell M.
Nesland, Jahn M.
Dybsjordl, Indrejit
Bormer, Ole
Hoie, Johan
Pihl, Alexander
Publicado en: Histology and histopathology
URI: http://hdl.handle.net/10201/17928
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 6
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol. 3, nº 3 (1988)



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