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http://hdl.handle.net/10201/17836
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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Smet, Peter | es |
dc.contributor.author | Rush, Robert A. | es |
dc.contributor.author | Straznicky, Charles | - |
dc.date.accessioned | 2011-01-17T12:39:27Z | - |
dc.date.available | 2011-01-17T12:39:27Z | - |
dc.date.issued | 1986 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/17836 | - |
dc.description.abstract | The generation and degeneration of sympathetic neurons in the third thoracic ganglion (segment 19) of the chick were studied between embryonic days (E) 7-18 using 3H-Thymidine autoradiography and routine cell counts. Cumulative radiolabelling experiments indicated that few sympathetic neurons were generated on E6-7. 10% of the sympathetic neurons were generated on E8 and a further 20% on E9. The final 70% of neurons completed the mitotic cycle between E10-12. Cell counts demonstrated that the neuronal population increased from 10,166 + 423 (mean 2 SEM) to 22,291 ? 767 between E8-10 and remained stable up to E14. The population subsequently declined by 37%, to 14,157 + 831, by E18. Pyknotic neurons were found at all stages of development, but were most apparent between E7-15. The effects of Nerve Cirowth Factor (NGF) on the number of both surviving and pyknotic neurons in the ganglion were also examined. E9 embryos treated with NGF from E5-8 showed a 57% increase in the number of sympathetic neurons. This increase therefore occurred prior to the decline in neuronal number and was not accompanied by a decrease in the number of visibly pyknotic neurons. It is therefore possible that early NGF treatment increases the number of sympathetic neurons through a mechanism other than the attenuation of cell death. | - |
dc.format | application/pdf | es |
dc.format.extent | 7 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Sympathetic neurons | es |
dc.subject | Nerve growth factor | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::612 - Fisiología | es |
dc.title | The thoracic sympathetic neurons of the chick, normal development and the effects of nerve growth factor | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol. 1, nº 4 (1986) |
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Fichero | Descripción | Tamaño | Formato | |
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The thoracic sympathetic neurons of the chick normal development and the effects of nerve growth factor.pdf | 567,96 kB | Adobe PDF | ![]() Visualizar/Abrir |
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