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| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Fuster, M. G. | - |
| dc.contributor.author | Moulefera, I. | - |
| dc.contributor.author | Montalbán, M. G. | - |
| dc.contributor.author | Pérez, J. | - |
| dc.contributor.author | Víllora, G. | - |
| dc.contributor.author | García, G. | - |
| dc.contributor.other | Facultad de Química | es |
| dc.date.accessioned | 2025-07-17T08:38:08Z | - |
| dc.date.available | 2025-07-17T08:38:08Z | - |
| dc.date.issued | 2022-10-26 | - |
| dc.identifier.citation | Molecules 2022, 27(21), 7264 | es |
| dc.identifier.issn | 1420-3049 | - |
| dc.identifier.uri | http://hdl.handle.net/10201/157481 | - |
| dc.description | © 2022 by the authors____ This document is the published version of a published work that appeared in final form in Molecules____ This document is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0 ____ To access the final edited and published work see: https://doi.org/10.3390/molecules27217264 | - |
| dc.description.abstract | When the [Ru(p-cymene)( -Cl)Cl]2 complex is made to react, in dichloromethane, with the following ligands: 2-aminobenzonitrile (2abn), 4-aminobenzonitrile (4abn), 2-aminopyridine (2ampy) and 4-aminopyridine (4ampy), after addition of hexane, the following compounds are obtained: [Ru(p-cymene)Cl2(2abn)] (I), [Ru(p-cymene)Cl2(4abn)] (II), [Ru(p-cymene)Cl2(2ampy] (III) and [Ru(pcymene) Cl2( -(4ampy)] (IV). All the compounds are characterized by elemental analysis of carbon, hydrogen and nitrogen, proton nuclear magnetic resonance, COSY 1H-1H, high-resolution mass spectrometry (ESI), thermogravimetry and single-crystal X-ray diffraction (the crystal structure of III is reported and compared with the closely related literature of II). The cytotoxicity effects of complexes were described for cervical cancer HeLa cells via 3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide (MTT) assay. The results demonstrate a low in vitro anticancer potential of the complexes. | - |
| dc.format | application/pdf | es |
| dc.format.extent | 11 | es |
| dc.language | eng | es |
| dc.publisher | MDPI | es |
| dc.relation | Ámbito del proyecto: nacional Agencia financiadora: Agencia estatal de investigación y Ministerio de Ciencia, Innovación y Universidades Convocatoria: 2020 Nombre del proyecto: BIOMATERIALES EN NANOINGENIERÍA: PRODUCCIÓN Y APLICACIONES EN TERAPIAS ANTICANCERÍGENA, ANTIBACTERIANA Y ANTIVIRAL Código o número del acuerdo de subvención: PID2020-113081RB-I00 | es |
| dc.rights | info:eu-repo/semantics/openAccess | es |
| dc.rights | Atribución 4.0 Internacional | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
| dc.subject | Ruthenium | es |
| dc.subject | Complexes | es |
| dc.subject | Cytotoxicity | es |
| dc.subject | Anticancer activity | es |
| dc.subject | HeLa | es |
| dc.subject | MTT assay | es |
| dc.title | Synthesis and Characterization of New Ruthenium (II) Complexes of Stoichiometry [Ru(p-Cymene)Cl2L] and Their Cytotoxicity against HeLa-Type Cancer Cells | es |
| dc.type | info:eu-repo/semantics/article | es |
| dc.relation.publisherversion | https://www.mdpi.com/1420-3049/27/21/7264 | - |
| dc.identifier.doi | https://doi.org/10.3390/molecules27217264 | - |
| dc.contributor.department | Ingeniería Química | es |
| Aparece en las colecciones: | Artículos | |
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