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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Hou, Huifang | - |
dc.contributor.author | Zheng, Miaoyun | - |
dc.contributor.author | Pan, Kai | - |
dc.contributor.author | Wang, Guodong | - |
dc.contributor.author | Li, Zongjin | - |
dc.contributor.author | Li, Qiong | - |
dc.date.accessioned | 2025-07-07T10:35:42Z | - |
dc.date.available | 2025-07-07T10:35:42Z | - |
dc.date.issued | 2025 | - |
dc.identifier.citation | Histology and Histopathology Vol. 40, nº07 (2025) | es |
dc.identifier.issn | 0213-3911 | - |
dc.identifier.issn | 1699-5848 | - |
dc.identifier.uri | http://hdl.handle.net/10201/157042 | - |
dc.description.abstract | Extracellular adenine nucleotides serve as crucial signaling molecules and influence a broad spectrum of physiological and pathological processes. CD73, the rate-limiting enzyme in the metabolism of extracellular adenine nucleotides, is ubiquitously expressed on various cell types, particularly stem cells. CD73+ mesenchymal stem cells (MSCs) have emerged as promising candidates for therapeutic applications due to their immunomodulatory and pro-regenerative properties. Numerous studies have highlighted the crucial role of CD73 in mediating tissue protection in myocardial infarction (MI). In this review, a brief overview of the cell type-specific expression, regulatory effects of CD73 on MSCs, and proangiogenic and immunomodulatory mechanisms is provided, with a focus on current findings concerning the protective functions of CD73 in the context of MI within the framework of stem cell therapy | es |
dc.format | application/pdf | es |
dc.format.extent | 11 | es |
dc.language | eng | es |
dc.publisher | Universidad de Murcia, Departamento de Biologia Celular e Histiologia | es |
dc.relation | Sin financiación externa a la Universidad | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Mesenchymal stem cells (MSCs) | es |
dc.subject | Myocardial infarction (MI) | es |
dc.subject | Angiogenesis | es |
dc.subject | Immune regulation | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología | es |
dc.title | Therapeutic potential of CD73+ mesenchymal stem cells for myocardial infarction and beyond | es |
dc.type | info:eu-repo/semantics/article | es |
dc.identifier.doi | https://doi.org/10.14670/HH-18-859 | - |
dc.contributor.department | Departamento de Biologia Celular e Histiologia | es |
Aparece en las colecciones: | Vol.40, nº7 (2025) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Hou-40-993-1003-2025.pdf | 2,62 MB | Adobe PDF | ![]() Visualizar/Abrir |
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