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Título: | An adverse effect of Ocrelizumab treatment in a patient with multiple sclerosis: a case report of necrotizing periodontitis |
Fecha de publicación: | 4-abr-2023 |
Editorial: | Gavin Publishers |
Cita bibliográfica: | Dentistry: Advanced Research, 2023, Vol.7 , N. 2: 203 |
ISSN: | Electronic: 2574-7347 |
Palabras clave: | Multiple sclerosis Necrotizing periodontitis Periodontal disease Periodontal treatment Periodontitis Relapsing remitting multiple sclerosis |
Resumen: | Multiple Sclerosis (MS) and Necrotizing Periodontitis (NP) are two diseases whose aetiologies and pathophysiologies do not appear to have a common link; however, treating MS with monoclonal antibodies and the decrease in humoral immunity that this entails can be a trigger or an aggravation in patients who present with quiescent NP. We describe a clinical case of NP, including clinical manifestations, treatment, and evolution during therapy with ocrelizumab and to review risk factors. A rapid progression of NP was evidenced. During the patient’s evolution, she suffered bilateral pneumonia due to coronavirus disease 2019, requiring treatment with corticosteroids and antibiotics, which led to clinical relief of her NP. Based on this case, we believe that regulated dental monitoring of patients with MS before, during, and after the administration of monoclonal antibodies may help prevent periodontal deterioration. |
Autor/es principal/es: | Montoya-Carralero, José María Sánchez-Pérez, Arturo Jornet-García, Alfonso Moya Villaescusa, María José |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Dermatología, Estomatología, Radiología y Medicina Física |
Versión del editor: | https://www.gavinpublishers.com/article/view/an-adverse-effect-of-ocrelizumab-treatment-in-a--patient-with-multiple-sclerosis-a-case-report-of-necrotizing-periodontitis |
URI: | http://hdl.handle.net/10201/143559 |
DOI: | https://doi.org/10.29011/2574-7347.100103 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 6 |
Derechos: | info:eu-repo/semantics/openAccess Atribución-CompartirIgual 4.0 Internacional |
Descripción: | © 2023 by the Authors & Gavin Publishers. This manuscript version is made available under the CC-BY-SA 4.0 license http://creativecommons.org/licenses/by-sa/4.0/ This document is the Published version of a Published Work that appeared in final form in Dentistry: Advanced Research. To access the final edited and published work see https://doi.org/10.29011/2574-7347.100103 |
Aparece en las colecciones: | Artículos: Dermatología, Estomatología, Radiología y Medicina Física |
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Fichero | Descripción | Tamaño | Formato | |
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2023.EM_RR.pdf | 1,1 MB | Adobe PDF | Visualizar/Abrir |
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