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https://doi.org/10.1016/j.brainresbull.2005.05.006
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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Legaz Pérez, Isabel | - |
dc.contributor.author | García López, Margarita | - |
dc.contributor.author | Medina, Loreta | - |
dc.contributor.other | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Ciencias Sociosanitarias | - |
dc.date.accessioned | 2024-07-12T08:50:55Z | - |
dc.date.available | 2024-07-12T08:50:55Z | - |
dc.date.issued | 2005-09-15 | - |
dc.identifier.citation | Brain Research Bulletin, 2005, Vol. 66, Issues 4–6, pp. 470-474 | es |
dc.identifier.issn | Print: 0361-9230 | - |
dc.identifier.uri | http://hdl.handle.net/10201/143060 | - |
dc.description | © 2005 Elsevier Inc. This document is the Published version of a Published Work that appeared in final form in Brain Research Bulletin. To access the final edited and published work see https://doi.org/10.1016/j.brainresbull.2005.05.006 | - |
dc.description.abstract | The aim of the present study was to investigate whether part of the calbindin-positive neurons of the claustral complex and piriform cortex originate in the subpallium. To that end, we prepared organotypic cultures of embryonic telencephalic slices, and applied the cell tracker CMTMR to the ventricular/subventricular zone of the lateral or medial ganglionic eminence. Following 48 h of incubation, we observed a number of CMTMR-labeled cells (showing red fluorescence) of subpallial origin in the claustral complex and piriform cortex. To know whether some of these cells of subpallial origin were calbindin-positive, we performed immunofluorescence for calbindin using an Alexa 488-conjugated secondary antiserum (green fluorescence). Our results showed that some of the CMTMR-labeled cells of subpallial origin in the claustral complex and piriform cortex are calbindin-positive (and possibly GABAergic). The subpallial origin of part of these cells was confirmed by observation of double labeled neurons in the claustral complex that expressed both Lhx6 mRNA (a marker of cells derived from the medial ganglionic eminence) and calbindin. Future studies will be required to analyze the existence of a subpopulation of non-GABAergic calbindin cells in the claustral complex and piriform cortex, and to know their origin. | es |
dc.format | application/pdf | es |
dc.format.extent | 5 | es |
dc.language | eng | es |
dc.publisher | Elsevier | - |
dc.relation | This work was supported by the Spanish Ministry of Science and Technology (CYCIT-FEDER; grants BFI2000-1359-C02-02 and BFI2003-06453-C02-02 to L.M.; fellowship FP2000-5943 to I.L.), the Spanish Ministry of Health-Institute Carlos III (FIS-FEDER grant 01/0057-02 to L.M. and Red CIEN-Nodo 318) and Séneca Foundation (grant PB/50/FS/02 to L.M.). | es |
dc.rights | info:eu-repo/semantics/embargoedAccess | es |
dc.subject | Interneurons | es |
dc.subject | Claustrum | es |
dc.subject | Endopiriform nucleus | es |
dc.subject | Tangential migration | es |
dc.subject | Lhx6 | es |
dc.title | Subpallial origin of part of the calbindin-positive neurons of the claustral complex and piriform cortex | es |
dc.type | info:eu-repo/semantics/article | es |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0361923005001693#aep-acknowledgment-id20 | - |
dc.embargo.terms | SI | - |
dc.identifier.doi | https://doi.org/10.1016/j.brainresbull.2005.05.006 | - |
Aparece en las colecciones: | Artículos: Ciencias Sociosanitarias |
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