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https://doi.org/10.6002/ect.2017.0302
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Título: | Patient sex in the setting of liver transplant in alcoholic liver disease |
Fecha de publicación: | jun-2019 |
Editorial: | Baskent University |
Cita bibliográfica: | Experimental and Clinical Transplantation, 2019, 17(3), pp. 355-362. |
ISSN: | Print: 1304-0855 Electronic: 2146-8427 |
Palabras clave: | Alcohol Alcoholic cirrhosis Human clinical toxicology Liver transplant Posttransplant survival |
Resumen: | Objectives: The aim of this study was to analyze alcoholic cirrhosis in women who were to undergo liver transplant, including their biochemical and clinical characteristics, main complications, survival rates, and main causes of death compared with men with alcoholic cirrhosis. Materials and Methods: Our study included 400 patients with alcoholic cirrhosis, which we divided according to sex and viral infections. Biochemical parameters and the presence and degree of ascites and encephalopathy, liver function status, and liver rejection and survivalrates were analyzed from 1 to 10 years and the main cause of death at 10 years. Results: Patients with nonviral alcoholic cirrhosis and liver transplant had significantly better survival rates (84.1%) at 1 year versus those with viral alcoholic cirrhosis (74.5%; P = .036). Men with nonviral alcoholic cirrhosis (14%) and women with hepatitis C virus (29%) had the lowest short-term survival rates. In long-term survival analysis, the lowest rate was observed in women with nonviral alcoholic cirrhosis (26.1%), and the highest rate was observed in women with hepatitis C virus (42.9%). Liver graft failure was one of the main causes of death in male patients (19.5%). Conclusions: Women with alcoholic cirrhosis showed a higher rate of ascites and encephalopathy but lower liver graft rejection than men with alcoholic cirrhosis. Survival rates were similar between men and women, although slightly lowerin women who had hepatitis C virus. |
Autor/es principal/es: | Legaz Pérez, Isabel Navarro Noguera, Elena Bolarín, Jose Miguel Campillo, Jose Antonio Moya, Rosa Luna, Aurelio Miras, Manuel Minguela, Alfredo Álvarez López, María Rocio Muro, Manuel |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Ciencias Sociosanitarias |
Versión del editor: | https://www.ectrx.org/detail/archive/2019/17/3/0/355/0 |
URI: | http://hdl.handle.net/10201/143041 |
DOI: | https://doi.org/10.6002/ect.2017.0302 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 8 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
Descripción: | © Baskent University 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Published version of a Published Work that appeared in final form in Experimental and Clinical Transplantation. To access the final edited and published work see https://doi.org/10.6002/ect.2017.0302 |
Aparece en las colecciones: | Artículos: Ciencias Sociosanitarias |
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