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Título: | Mural Endocarditis: The GAMES Registry Series and Review of the Literature |
Fecha de publicación: | 26-jul-2021 |
Editorial: | Springer |
Cita bibliográfica: | Infect Dis Ther. 2021, 10(4): 2749 - 2764 |
ISSN: | Print: 2193-8229 Electronic: 2193-6382 |
Palabras clave: | Endocarditis Mural Non-valvular endocarditis |
Resumen: | Introduction: Mural infective endocarditis (MIE) is a rare type of endovascular infection. We present a comprehensive series of patients with mural endocarditis. Methods: Patients with infectious endocarditis (IE) from 35 Spanish hospitals were prospectively included in the GAMES registry between 2008 and 2017. MIEs were compared to non-MIEs. We also performed a literature search for cases of MIE published between 1979 and 2019 and compared them to the GAMEs series. Results: Twenty-seven MIEs out of 3676 IEs were included. When compared to valvular IE (VIE) or device associated IE (DIE), patients with MIE were younger (median age 59 years, p \ 0.01). Transplantation (18.5% versus 1.6% VIE and 2% DIE, p \ 0.01), hemodialysis (18.5% versus 4.3% VIE and 4.4% DIE, p = 0.006), catheter source (59.3% versus 9.7% VIE and 8.8% DIE, p \ 0.01) and Candida etiology (22.2% versus 2% DIE and 1.2% VIE, p \ 0.01) were more common in MIE, whereas the Charlson Index was lower (4 versus 5 in non- MIE, p = 0.006). Mortality was similar.MIE from the literature shared many characteristics with MIE from GAMES, although patients were younger (45 years vs. 56 years, p \ 0.001), the Charlson Index was lower (1.3 vs. 4.3, p = 0.0001), catheter source was less common (13.9% vs. 59.3%) and there were more IVDUs (25% vs. 3.7%). S. aureus was the most frequent microorganism (50%, p = 0.035). Systemic complications were more common but mortality was similar. Conclusion: MIE is a rare entity. It is often a complication of catheter use, particularly in immunocompromised and hemodialysis patients. Fungal etiology is common. Mortality is similar to other IEs. |
Autor/es principal/es: | Gutiérrez-Villanueva, Andrea Muñoz, Patricia Delgado-Montero, Antonia Olmedo-Samperio, María Alarcón, Arístides de Gutiérrez-Carretero, Encarnación Zarauza, Jesús García i Pares, Delia Goenaga, Miguel Ángel Ojeda-Burgos, Guillermo Goikoetxea-Agirre, Ane Josune Reguera-Iglesias, José Mª Ramos, Antonio Fernández-Cruz, Ana Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES)S) García-Vázquez, Elisa |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Medicina Interna |
Forma parte de: | This manuscript is based on work that has been previously presented as an oral communication at the VIIIth Congress of SEICAV (Spanish Society of Cardiovascular Infections) in Madrid, September 2019. |
Versión del editor: | https://link.springer.com/article/10.1007/s40121-021-00490-y |
URI: | http://hdl.handle.net/10201/142758 |
DOI: | https://doi.org/10.1007/s40121-021-00490-y |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 16 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
Descripción: | © 2021 The Author(s). This manuscript version is made available under the CC-BY-NC 4.0 license http://creativecommons.org/licenses/by-nc/4.0/. This document is the Acceptedversion of a Published Work that appeared in final form in Infectious Diseases and Therapy. To access the final edited and published work see https://doi.org/10.1007/s40121-021-00490-y |
Aparece en las colecciones: | Artículos: Medicina |
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