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https://doi.org/10.1016/j.jacc.2018.03.534
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Título: | Infective endocarditis in patients with bicuspid aortic valve or mitral valve prolapse |
Fecha de publicación: | 19-jun-2018 |
Cita bibliográfica: | Journal of the American College of Cardiology. 2018, vol. 71(24): 2731-2740 |
ISSN: | Print: 0735-1097 Electronic: 1558-3597 |
Resumen: | BACKGROUND: There is little information concerning infective endocarditis (IE) in patients with bicuspid aortic valve (BAV) or mitral valve prolapse (MVP). Currently, IE antibiotic prophylaxis (IEAP) is not recommended for these conditions. OBJECTIVES: This study sought to describe the clinical and microbiological features of IE in patients with BAV and MVP and compare them with those of IE patients with and without IEAP indication, to determine the potential benefit of IEAP in these conditions. METHODS: This analysis involved 3,208 consecutive IE patients prospectively included in the GAMES (Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España) registry at 31 Spanish hospitals. Patients were classified as high-risk IE with IEAP indication (high-risk group; n ¼ 1,226), low- and moderate-risk IE without IEAP indication (low/moderate-risk group; n ¼ 1,839), and IE with BAV (n ¼ 54) or MVP (n ¼ 89). RESULTS: BAV and MVP patients had a higher incidence of viridans group streptococci IE than did high-risk group and low/moderate-risk group patients (35.2% and 39.3% vs. 12.1% and 15.0%, respectively; all p < 0.01). A similar pattern was seen for IE from suspected odontologic origin (14.8% and 18.0% vs. 5.8% and 6.0%; all p < 0.01). BAV and MVP patients had more intracardiac complications than did low/moderate-risk group (50% and 47.2% vs. 30.6%, both p < 0.01) patients and were similar to high-risk group patients. CONCLUSIONS: IE in patients with BAV and MVP have higher rates of viridans group streptococci IE and IE from suspected odontologic origin than in other IE patients, with a clinical profile similar to that of high-risk IE patients. Our findings suggest that BAV and MVP should be classified as high-risk IE conditions and the case for IEAP should be reconsidered. (J Am Coll Cardiol 2018;71:2731–40) © 2018 by the American College of Cardiology Foundation. |
Autor/es principal/es: | Zegri-Reiriz, Isabel Alarcón, Arístides de Muñoz, Patricia Martínez Sellés, Manuel González-Ramallo, Victor Miro, Jose M. Falces, Carles Gonzalez Rico, Claudia Kortajarena Urkola, Xabier Lepe, José Antonio Rodriguez Álvarez, Regino Reguera Iglesias, Jose Maria Navas, Enrique Dominguez, Fernando Garcia-Pavia, Pablo García-Vázquez, Elisa Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES) |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Medicina Interna |
Versión del editor: | https://www.sciencedirect.com/science/article/pii/S073510971834556X |
URI: | http://hdl.handle.net/10201/142699 |
DOI: | https://doi.org/10.1016/j.jacc.2018.03.534 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 10 |
Derechos: | info:eu-repo/semantics/embargoedAccess |
Descripción: | ©2020. Elsevier Inc. Todos los derechos reservados. This document is the Published, version of a Published Work that appeared in final form in Journal of the American College of Cardiology. To access the final edited and published work see https://doi.org/10.1016/j.jacc.2018.03.534 |
Aparece en las colecciones: | Artículos: Medicina |
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