Por favor, use este identificador para citar o enlazar este ítem:
https://doi.org/10.3390/ijerph18031018
Twittear
Título: | Treatment of stage 2 medication-induced osteonecrosis of the jaw: a case series |
Fecha de publicación: | 24-ene-2021 |
Editorial: | MDPI |
Cita bibliográfica: | Int. J. Environ. Res. Public Health 2021, 18(3), 1018 |
ISSN: | Print: 1661-7827 Electronic: 1660-4601 |
Palabras clave: | Osteonecrosis Medication-induced maxillary osteonecrosis Bisphosphonates Denosumab Osteonecrosis treatment |
Resumen: | Medication-induced jaw osteonecrosis (MRONJ) is a rare and serious disease with a negative impact on patients’ quality of life, whose exact cause remains unclear and which may have a multifactorial origin. Although there are different therapeutic protocols, there is still no consensus. This case series evaluated three patients diagnosed with staged 2 MRONJ treated at the University of Murcia dental clinic according to the protocols described by the Spanish Society of Oral and Maxillofacial Surgery and the American Association of Oral and Maxillofacial Surgeons. Within 12 months of the application of therapeutic protocols, the lesions were completely healed in all cases. Radiography showed slow but progressive healing with normal bone structure. Conservative treatment with antibiotics, chlorhexidine rinses and minimally invasive surgical intervention with necrotic bone resection is effective in treating stage 2 of MRONJ. In cases of refractory osteonecrosis, the application of platelet and leukocyte-rich fibrin (PRF-L) in the surgical approach improves the outcome in soft tissue healing and bone regeneration but further research is needed to confirm its effectiveness. |
Autor/es principal/es: | Pardo-Zamora, Guillermo Martínez, Yanet Moreno, José Antonio Ortiz Ruiz, Antonio José |
Versión del editor: | https://www.mdpi.com/1660-4601/18/3/1018 |
URI: | http://hdl.handle.net/10201/142456 |
DOI: | https://doi.org/10.3390/ijerph18031018 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 18 |
Derechos: | info:eu-repo/semantics/openAccess Atribución 4.0 Internacional |
Descripción: | © 2021 by the authors. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/. This document is the Published version of a Published Work that appeared in final form in International Journal of Environmental Research and Public Health. To access the final edited and published work see https://doi.org/10.3390/ijerph18031018 |
Aparece en las colecciones: | Artículos: Dermatología, Estomatología, Radiología y Medicina Física |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
ijerph-18-01018-v3.pdf | 7,17 MB | Adobe PDF | Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons