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Título: Biocompatibility of a HA/β-TCP/C scaffold as a pulp-capping agent for vital pulp treatment: an in vivo study in rat molars
Fecha de publicación: 8-abr-2021
Editorial: MDPI
Cita bibliográfica: International Journal of Environmental Research and Public Health, 2021, Vol. 18 (8), 3936
ISSN: Electronic: 1660-4601
Print: 1661-7827
Palabras clave: Beta-tricalcium phosphate
Hydroxyapatite
Mineral trioxide aggregate
Vital pulp therapy
Scaffolds
Resumen: Bioceramic materials possess desirable biological properties, highlighting their non-reactivity and osteoconductivity. Their use has been extended in vital pulp treatment. The purpose of this study was to evaluate and compare the effects of beta-tricalcium phosphate (β-TCP), hydroxyapatite (HA), and collagen (C) scaffold with mineral trioxide aggregate (MTA) on the vital pulp of rat molars. Thirty-two molars of Sprague–Dawley rats underwent direct pulp capping with β-TCP/HA/C (n = 16) and MTA (n = 16). After 30 days, the following parameters were evaluated in the tested samples: the degree of pulp inflammation and pulp vitality, the presence of reparative dentin, the homogeneity of the odontoblastic layer, and the presence of pulp fibrosis. No statistically significant differences were observed between HA/β-TCP/C and MTA in terms of the degree of inflammation (p = 0.124). Significant differences were found in reparative dentin formation between the treatment groups (p = 0.0005). Dentin bridge formation was observed in the MTA-treated group. The local action of HA/β-TCP/C is similar to that of MTA when used as an agent for pulp vital treatment in terms of absence of inflammation and maintenance of pulp vitality, although there are significant differences between both materials regarding the formation of dentin bridges.
Autor/es principal/es: Guerrero Gironés, Julia
Alcaina Lorente, Antonio
Ortiz Ruiz, Clara
Ortiz Ruiz, Eduardo
Pecci Lloret, María P.
Ortiz Ruiz, Antonio José
Rodríguez Lozano, Francisco Javier
Pecci Lloret, Miguel R.
Facultad/Departamentos/Servicios: Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Dermatología, Estomatología, Radiología y Medicina Física
Versión del editor: https://www.mdpi.com/1660-4601/18/8/3936
URI: http://hdl.handle.net/10201/142453
DOI: https://doi.org/10.3390/ijerph18083936
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 9
Derechos: info:eu-repo/semantics/openAccess
Atribución 4.0 Internacional
Descripción: © 2021 by the authors. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Published version of a Published Work that appeared in final form in International Journal of Environmental Research and Public Health. To access the final edited and published work see https://doi.org/10.3390/ijerph18083936
Aparece en las colecciones:Artículos: Dermatología, Estomatología, Radiología y Medicina Física

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