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Título: Widespread doublecortin expression in the cerebral cortex of the octodon degus
Fecha de publicación: 29-abr-2021
Editorial: Frontiers Media
Cita bibliográfica: Frontiers Neuroanatomy April 2021, vol. 15 656882
ISSN: Electronic: 1662-5129
Materias relacionadas: CDU::5 - Ciencias puras y naturales
Palabras clave: Octodon degus
Cerebral cortex
Cortical atlas
Doublecortin
Limbic system
Resumen: It has been demonstrated that in adulthood rodents show newly born neurons in the subgranular layer (SGL) of the dentate gyrus (DG), and in the subventricular zone (SVZ). The neurons generated in the SVZ migrate through the rostral migratory stream (RMS) to the olfactory bulb. One of the markers of newly generated neurons is doublecortin (DCX). The degu similarly shows significant numbers of DCX-labeled neurons in the SGL, SVZ, and RMS. Further, most of the nuclei of these DCX-expressing neurons are also labeled by proliferating nuclear antigen (PCNA) and Ki67. Finally, whereas in rats and mice DCX-labeled neurons are predominantly present in the SGL and SVZ, with only a few DCX neurons present in piriform cortex, the degu also shows significant numbers of DCX expressing neurons in areas outside of SVZ, DG, and PC. Many areas of neocortex in degu demonstrate DCX-labeled neurons in layer II, and most of these neurons are found in the limbic cortices. The DCX-labeled cells do not stain with NeuN, indicating they are immature neurons.
Autor/es principal/es: Van Groen, Thomas
Kadish, Inga
Popovic, Natalija
Caballero Bleda, María
Baño-Otalora, Beatriz
Rol, María Ángeles
Madrid, Juan Antonio
Popovic, Miroljub
Facultad/Departamentos/Servicios: Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Anatomía Humana y Psicobiología
Versión del editor: https://www.frontiersin.org/articles/10.3389/fnana.2021.656882/full
URI: http://hdl.handle.net/10201/142383
DOI: https://doi.org/10.3389/fnana.2021.656882
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 11
Derechos: info:eu-repo/semantics/openAccess
Atribución 4.0 Internacional
Descripción: © 2021 van Groen, Kadish, Popović, Caballero Bleda, Baño-Otalora, Rol, Madrid and Popović. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/. This document is the Published version of a Published Work that appeared in final form in Frontiers in Neuroanatomy. To access the final edited and published work see https://doi.org/10.3389/fnana.2021.656882
Aparece en las colecciones:Artículos: Anatomía Humana y Psicobiología

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