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https://doi.org/10.1016/S1885-5857(10)70059-1
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Gimeno, Juan Ramón | - |
dc.contributor.author | Oliva, María José | - |
dc.contributor.author | Lacunza, Javier | - |
dc.contributor.author | García Alberola, Arcadio | - |
dc.contributor.author | Sabater Molina, María | - |
dc.contributor.author | Martínez Sánchez, Juan José | - |
dc.contributor.author | Saura, Daniel | - |
dc.contributor.author | Romero, Antonio | - |
dc.contributor.author | Valdés, Mariano | - |
dc.contributor.other | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Ciencias Sociosanitarias | - |
dc.date.accessioned | 2024-02-12T11:56:55Z | - |
dc.date.available | 2024-02-12T11:56:55Z | - |
dc.date.issued | 2009-09-17 | - |
dc.identifier.citation | Revista Española de Cardiología; 63(3) 2010: 268-276 | es |
dc.identifier.issn | Electrónico: 1579-2242 | - |
dc.identifier.issn | Papel: 0300-8932 | - |
dc.identifier.uri | http://hdl.handle.net/10201/139283 | - |
dc.description | ©2009. This document is the Accepted, version of a Published Work that appeared in final form in Revista Española de Cardiología. To access the final edited and published work see https://doi.org/10.1016/S1885-5857(10)70059-1 | - |
dc.description.abstract | Introduction and objectives Cardiomyopathy and channelopathy are major causes of sudden death (SD). The little information available on the context in which SD occurs has come from only a few referral centers. The objective was to investigate the circumstances surrounding SD in families with inherited heart disease.. Methods. The study included 152 SD patients (mean age, 43[19] years) from 103 families. The reasons for inclusion were resuscitated SD in 7%, recent SD in 8%, and a diagnosis of cardiomyopathy or channelopathy in a living relative in 72%. Also, 13% were athletes. Family trees were constructed and each death’s circumstances were recorded. Autopsy and medical records were reviewed. Results. Overall, 18% of SDs occurred during physical exercise, 32% during normal daily activities, and 37% during rest or sleep. There was a significant association between male sex and SD: 111 males (73.0%) versus 41 females (27.0%; P=.03). Exercise-related SD was associated with young age (P=.01). The percentage of SDs associated with exercise, stress, or normal daily activities was significantly greater with cardiomyopathy than channelopathy (61% vs 41%, P=.057). All athletes were male and the majority died during exercise (50% vs 11% of non-athletes; P=.0002). Patients with Brugada syndrome had the highest percentage of SDs during rest or sleep (ie, 47%). No clear trigger could be identified in 33%. Conclusions. SD was common in inherited heart disease, which accounted for a significant number of cases. Males clearly predominated over females (ratio, 3:1) among SD cases (irrespective of pathological type). Most SDs occurred during exercise or normal daily activities in cardiomyopathies and during rest or sleep in channelopathies. The percentage of exercise-related SDs (i.e. 18%) was higher than expected. | es |
dc.format | application/pdf | es |
dc.format.extent | 9 | es |
dc.language | eng | es |
dc.publisher | Elsevier | - |
dc.relation | This work has been made thanks to a grant from Fundación Española del Corazón and Coca-Cola Spain (2006 and 2007) and has been supported by a partial financial support from la Red de Investigación Cardiovascular RECAVA from Instituto de Salud Carlos III. | es |
dc.rights | info:eu-repo/semantics/embargoedAccess | es |
dc.subject | Inherited heart disease | - |
dc.subject | Cardiomyopathy | - |
dc.subject | Channelopathy | - |
dc.subject | Sudden death | - |
dc.title | Characteristics of sudden death in inherited heart disease | es |
dc.type | info:eu-repo/semantics/article | es |
dc.embargo.terms | Si | - |
dc.identifier.doi | https://doi.org/10.1016/S1885-5857(10)70059-1 | - |
Aparece en las colecciones: | Artículos: Ciencias Sociosanitarias |
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RECaceptado2009-2010.pdf | 98,42 kB | Adobe PDF | ![]() Visualizar/Abrir Solicitar una copia |
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