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10.1016/j.fsi.2016.11.025
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Título: | Terminal carbohydrates abundance, immune related enzymes, bactericidal activity and physico-chemical parameters of the Senegalese sole (Solea senegalensis, Kaup) skin mucus |
Fecha de publicación: | 9-nov-2016 |
Fecha de defensa / creación: | 2016 |
Editorial: | Academic Press Ltd – Elsevier Science Ltd |
Cita bibliográfica: | Fish & Shellfish Immunology 60 (2017) 483e491 |
Palabras clave: | Skin mucus, Bactericidal activity, Physico-chemical parameters, Senegalese sole (Solea senegalensis, Kaup), Teleosts |
Resumen: | Recently, interest in mucosal surfaces, more specifically fish skin and its secreted mucus, has greatly increased among immunologists. The abundance of terminal carbohydrates, several enzymes (proteases, lysozyme, peroxidase, alkaline phosphatase, esterases and ceruloplasmin), bactericidal activity against fish pathogenic and non-pathogenic bacteria and several physico-chemical parameters (protein concentration, pH, conductivity, redox potential, osmolarity, density and viscosity) in the skin mucus of Senegalese sole (Solea senegalensis, Kaup) have been evaluated. Present results evidence the abundance of N-acetylneuraminic acid, mannose, glucose and N-acetyl-galactosamine in skin mucus. The levels of lysozyme, proteases, esterases and alkaline phosphatase were very similar (from 20 to 30 Units mg 1 protein). However, 93 Units mg 1 protein were detected of ceruloplasmin and only 4 0 88 Units mg 1 protein of peroxidase. Skin mucus of S. senegalensis showed high bactericidal activity against the tested pathogen bacteria but weak activity against non-pathogenic bacteria. Finally, a clear relationship between mucus density and temperature was detected, while viscosity showed a direct shear- and temperature-dependent behaviour. These results could be useful for better understanding the role of the skin mucus as a key component of the innate immune system, as well as, for elucidating possible relationships between biological and physico-chemical parameters and disease susceptibility. |
Autor/es principal/es: | Collado-González, Mar Guardiola, Francisco A. Cuartero, María Díaz Baños, F. Guillermo Cuesta, Alberto Moriñigo, Miguel Angel Esteban, M. Angeles |
Facultad/Departamentos/Servicios: | Facultad de biología. Dep Biología Celular e Histología |
URI: | http://hdl.handle.net/10201/139186 |
DOI: | 10.1016/j.fsi.2016.11.025 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 9 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NoDerivatives 4.0 Internacional |
Aparece en las colecciones: | Artículos: Biología Celular e Histología |
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FishShelfishImmunol2017_Guardiola.pdf | 547,65 kB | Adobe PDF | Visualizar/Abrir |
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