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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Collado González, María del Mar | - |
dc.contributor.author | Montalbán, Mercedes G. | - |
dc.contributor.author | Peña García, Jorge | - |
dc.contributor.author | Pérez Sánchez, Horacio | - |
dc.contributor.author | Víllora, Gloria | - |
dc.contributor.author | Díaz Baños, F. Guillermo | - |
dc.contributor.other | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU:: Biología Celular e Histología | - |
dc.date.accessioned | 2024-02-09T20:48:18Z | - |
dc.date.available | 2024-02-09T20:48:18Z | - |
dc.date.issued | 2016-12-24 | - |
dc.identifier.citation | Carbohydrate Polymers 161, 2017: 63-70 | es |
dc.identifier.issn | Print: 0144-8617 | - |
dc.identifier.issn | Electronic: 1879-1344 | - |
dc.identifier.uri | http://hdl.handle.net/10201/139155 | - |
dc.description | ©2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Accepted, version of a Published Work that appeared in final form in Carbohydrate Polymers. To access the final edited and published work see http://dx.doi.org/10.1016/j.carbpol.2016.12.043 | - |
dc.description.abstract | Chitosan is a biocompatible polysaccharide with positive Z potential which can stabilize negative charged nanoparticles. Silk fibroin nanoparticles and citrate gold nanoparticles, both with negative Z potential, but they form aggregates at physiological ionic strength. In this work, we study the behavior of chitosan in solution when the ionic strength of the medium is increased and how the concentration of chitosan and the proportion of the two components (chitosan and AuNP or SFN) significantly affect the stability and size of the nanocomposites formed. In addition to experimental measurements, molecular modeling were used to gain insight into how chitosan interacts with silk fibroin monomers, and to identify the main energetic interactions involved in the process. The optimum values for obtaining the smallest and most homogeneous stable nanocomposites were obtained and two different ways of organization through which chitosan may exert its stabilizing effect were suggested. | es |
dc.format | application/pdf | es |
dc.format.extent | 8 | es |
dc.language | eng | es |
dc.publisher | Elsevier | es |
dc.relation | This work was partially supported by the European Commission (FEDER/ERDF) and the Spanish MINECO (Ref. CTQ2011-25613 and Ref. CTQ2014-57467-R), the Seneca Foundation of Science and Technology of Murcia (Projects 19499/PI/14 and 18946/JLI/13), the supercomputing infrastructure of the NLHPC (ECM-02) and the computing facilities of Extremadura Research Centre for Advanced Technologies (CETA CIEMAT). The authors also thank- fully acknowledge the computer resources and the technical support provided by the Plataforma Andaluza de Bioinformática of the University of Málaga. Mercedes G. Montalbán acknowledges support from Spanish MINECO (FPI grant, BES-2012-053267 | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights | Attribution-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nd/4.0/ | * |
dc.subject | Chitosan | es |
dc.subject | Gold nanoparticles | - |
dc.subject | Silk fibroin nanoparticles | - |
dc.subject | Aggregation-Stabilizing effect | - |
dc.subject | Dynamic light scattering | - |
dc.subject | Molecular modeling | - |
dc.title | Chitosan as stabilizing agent for negatively charged nanoparticles | es |
dc.type | info:eu-repo/semantics/article | es |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0144861716314175?via%3Dihub | es |
dc.identifier.doi | http://dx.doi.org/10.1016/j.carbpol.2016.12.043 | - |
Aparece en las colecciones: | Artículos: Biología Celular e Histología |
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CarbPolym2016_ColladoGonzalez.pdf | 754,6 kB | Adobe PDF | Visualizar/Abrir |
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