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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Rodríguez Lozano, Francisco Javier | - |
dc.contributor.author | Oñate Sánchez, Ricardo E. | - |
dc.contributor.author | Ferreira, Cláudio M.A. | - |
dc.contributor.author | Sassone, Luciana M. | - |
dc.contributor.author | Gonçalves, Alexia S. | - |
dc.contributor.author | Carvalho, Jorge José de | - |
dc.contributor.author | Tomás-Catalá, Christopher J. | - |
dc.contributor.author | García-Bernal, David | - |
dc.contributor.author | Nogueira Leal Silva, Emmanuel João | - |
dc.date.accessioned | 2024-02-06T07:47:53Z | - |
dc.date.available | 2024-02-06T07:47:53Z | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | http://hdl.handle.net/10201/138681 | - |
dc.description | Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. © Te Author(s) 2019 | - |
dc.description.abstract | The purpose of this work was to evaluate the physicochemical properties, the cytotoxicity and in vivo biocompatibility of MTA Repair HP (MTA HP) and White MTA (WMTA). The setting time, fow, radiopacity and water solubility were assessed. To the cytotoxicity assay, primary human osteoblast cells were exposed to several dilutions of both materials eluates. MTT assay, apoptosis assay and cell adhesion assay were performed. The in vivo biocompatibility was evaluated through histological analysis using diferent staining techniques. No diferences were observed between MTA HP and WMTA for setting time, radiopacity, solubility and water absorption (P >0.05). However, MTA HP showed a signifcantly higher fow when compared to WMTA (P<0.05). Cell viability results revealed that the extracts of WMTA and MTA HP promoted the viability of osteoblasts. After incubation of cells with the endodontic cement extracts, the percentage of apoptotic or necrotic cells was very low (<3%). Furthermore, SEM results showed a high degree of cell proliferation and adhesion on both groups. MTA HP showed similar in vivo biocompatibility to the WMTA and the control group in all time-points. The MTA HP presented adequate physicochemical and biological properties with improved fow ability when compared to WMTA. Such improved fow ability may be a result of the addition of a plasticizing agent and should be related to an improvement in the handling of MTA HP. | en |
dc.format | application/pdf | es |
dc.language | eng | es |
dc.relation | This study is partially funded by FAPERJ, CNPq and by Instituto de Salud Carlos III (ISCIII) and the Spanish Net of Cell Therapy (TerCel), RETICS subprogram of the I + D + I 2013–2016 Spanish National Plan, project “RD16/0011/0001” funded by ISCIII and co-founded by FEDER “una manera de hacer Europa”. | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights | Attribution 4.0 Internacional | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject.other | Medicina | es |
dc.title | Physicochemical, cytotoxicity and in vivo biocompatibility of a highplasticity calcium-silicate based material | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Artículos: Dermatología, Estomatología, Radiología y Medicina Física |
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APORTACIÓN 4.pdf | Artículo | 3,67 MB | Adobe PDF | Visualizar/Abrir |
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