Por favor, use este identificador para citar o enlazar este ítem:
https://doi.org/10.1002/jctb.7462
Twittear
Registro completo de metadatos
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Montiel, M.C. | - |
dc.contributor.author | Serrano-Arnaldos, M. | - |
dc.contributor.author | Yagüe, C. | - |
dc.contributor.author | Ortega-Requena, S. | - |
dc.contributor.author | Máximo, F. | - |
dc.contributor.author | Bastida, J. | - |
dc.contributor.other | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Ingeniería Química | es |
dc.date.accessioned | 2024-02-01T15:18:00Z | - |
dc.date.available | 2024-02-01T15:18:00Z | - |
dc.date.issued | 2023-06-10 | - |
dc.identifier.citation | Journal of Chemical Technology and Biotechnology | es |
dc.identifier.issn | 0268-2575 | - |
dc.identifier.issn | 1097-4660 | - |
dc.identifier.uri | http://hdl.handle.net/10201/138450 | - |
dc.description.abstract | BACKGROUND: As a result of the ban on whaling, there has been a shortage of spermaceti, a natural product with applications in cosmetics and pharmaceuticals. A green and sustainable process for the biocatalytic synthesis of a wax ester mixture analogue to natural spermaceti is presented in this paper. RESULTS: Immobilization of Candida antarctica lipase B by covalent binding to Purolite® Lifetech™ ECR8285 allowed for an immobilized derivative with 124.5 mg protein/g support (69.3% protein immobilization yield) that maintains 100% of its enzymatic activity after 12 months of cold storage and presents negligible loses of activity after 9 consecutive reaction cycles. The optimization of the synthesis process in a batch reactor resulted in conditions that, at 70 °C, 350 rpm, and 1.25% w/w of biocatalyst, achieved a conversion of 97% after 1 h of reaction. The simulation of a spermaceti production plant was carried out using the process simulation software aspenONE suite v10. The plant was designed for a continuous operation during 9 h per day, with a reactor of 20.25 L of working volume and a residence time of 1 h. The production of this plant would be 173.25 kg spermaceti/day, with a product purity of 99.55%. CONCLUSION: The main novelty of this work is the design of a spermaceti production plant, using the most sustainable methodologies and resulting in a product with exceptional characteristics and minimal waste generation. Moreover, a new lipase immobilized derivative is also described. The good values of sustainability indicators point to the viability of its industrial implementation. | es |
dc.format | application/pdf | es |
dc.format.extent | 10 | es |
dc.language | eng | es |
dc.relation | Organismo Financiador: Ministerio de Ciencia, Innovación y Universidades. Convocatoria: PROYECTOS DE I+D+i «RETOS INVESTIGACIÓN» 2018, Proyecto: PROCESOS SOSTENIBLES PARA LA SINTESIS BIOCATALITICA DE ESTERES RAMIFICADOS. Código: RTI2018-094908-B-I00 | es |
dc.rights | info:eu-repo/semantics/embargoedAccess | es |
dc.subject | CalB lipase | es |
dc.subject | Enzyme immobilization | es |
dc.subject | Green metrics | es |
dc.subject | Plant simulation | es |
dc.subject | Process optimization | es |
dc.subject | Wax esters | es |
dc.title | Development of an industrial sustainable process for wax esters production: enzyme immobilization, process optimization, and plant simulation | es |
dc.type | info:eu-repo/semantics/article | es |
dc.relation.publisherversion | https://onlinelibrary.wiley.com/doi/epdf/10.1002/jctb.7462 | es |
dc.embargo.terms | Si | - |
dc.identifier.doi | https://doi.org/10.1002/jctb.7462 | - |
Aparece en las colecciones: | Artículos: Ingeniería Química |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
J of Chemical Tech Biotech - 2023 - Montiel - Development of an industrial sustainable process for wax esters production .pdf | 889,68 kB | Adobe PDF | Visualizar/Abrir Solicitar una copia |
Los ítems de Digitum están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.