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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Camacho Alonso, Fabio | - |
dc.contributor.author | García Carrillo, Nuria | - |
dc.contributor.author | Buendía, Antonio Julian | - |
dc.contributor.author | Navarro, José Antonio | - |
dc.contributor.author | Peñarrocha Oltra, David | - |
dc.contributor.author | Peñarrocha Diago, Miguel | - |
dc.contributor.author | Lacal Luján, José | - |
dc.contributor.other | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Dermatología, Estomatología, Radiología y Medicina Física | es |
dc.date.accessioned | 2024-01-31T17:50:43Z | - |
dc.date.available | 2024-01-31T17:50:43Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Oral Diseases 2021; 27(6):1580-1589 | es |
dc.identifier.issn | 1354-523X | - |
dc.identifier.uri | http://hdl.handle.net/10201/138324 | - |
dc.description.abstract | Objectives: To use tissue engineering muscle repair (TEMR) for regenerating the lingual musculature of hemiglossectomized rats using neonatal myoblasts (NM) on porcine acellular urinary bladder matrix (AUBM). Material and Methods: The study used 80 male rats. A volumetric muscle loss (VML) injury was created on the left side of the tongue. The rats were randomized into four groups: Group 1 (AUBM + myoblasts); Group 2 (AUBM); Group 3 (myoblasts); and Group 4 (control). NM were obtained from neonatal rats. The animals were weighed on day 0 and just before euthanasia. Five rats in each group were euthanized at days 2, 14, 28, and 42; the tongues were prepared for morphometric analysis, postoperative left hemitongue weight, and immunohistochemical analysis (desmin, CD-31, and anti-neurofilament). Results: The weight gain from greatest to least was as follows: AUBM + myoblasts > myoblasts > AUBM > control. The tongue dorsum occupied by VML, and difference in mg between control side and intervened side from least to great was as follows: AUBM + myoblasts < myoblasts < AUBM < control. The order from highest to lowest antibody positivity was as follows: AUBM + myoblasts > myoblasts > AUBM > control. Conclusion: The use of porcine AUBM and NM for the regeneration of lingual musculature was found to be an effective TEMR treatment for repairing tongue VML injury. | es |
dc.format | application/pdf | es |
dc.format.extent | 10 | es |
dc.language | eng | es |
dc.publisher | Wiley | es |
dc.relation | Sin financiación externa a la Universidad | es |
dc.rights | info:eu-repo/semantics/embargoedAccess | es |
dc.subject | Hemiglossectomized tongues | es |
dc.subject | Neonatal myoblasts | es |
dc.subject | Porcine acellular urinary bladder matrix | es |
dc.subject | Tissue engineering muscle repair | es |
dc.subject | Volumetric muscle loss | es |
dc.subject.other | CDU::5 - Ciencias puras y naturales | es |
dc.title | Regeneration of lingual musculature in rats using myoblasts over porcine bladder acellular matrix | es |
dc.type | info:eu-repo/semantics/article | es |
dc.embargo.terms | Si | - |
dc.identifier.doi | https://doi.org/10.1111/odi.13674 | - |
Aparece en las colecciones: | Artículos: Dermatología, Estomatología, Radiología y Medicina Física |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Oral Diseases - 2020 - Camacho‐Alonso - Regeneration of lingual musculature in rats using myoblasts over porcine bladder.2021 (27).pdf | 1,52 MB | Adobe PDF | Visualizar/Abrir Solicitar una copia |
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