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Título: | Development and economic evaluation of an eco-friendly biocatalytic synthesis of emollient esters. |
Fecha de defensa / creación: | 2019 |
Editorial: | Springer |
Cita bibliográfica: | Bioprocess and Biosystems Engineering, Volume 325, 10 January 2021, Pages 91-99 |
ISSN: | Print: 1615-7591 Electrónico: 1615-7605 |
Materias relacionadas: | CDU::5 - Ciencias puras y naturales::54 - Química |
Palabras clave: | Candida antarctica Cost assessment Solvent-free Spermaceti Thermomyces lanuginosus |
Resumen: | During the last decades the understanding and prospects of enzyme-catalysed reactions have been massively widened and there are a number of implemented large-scale enzymatic processes mainly based in the use of commercial biocatalysts. As it might happen that the same process can be successfully carried out by different commercial lipases, the election of the biocatalyst must rely on productivity and economic considerations. This work presents productiveness and direct operation cost evaluation as a key tool for the selection between two commercial lipase catalysts, the versatile but expensive Novozym® 435 and a much more economical option, Lipozyme® TL IM, in the synthesis of spermaceti, a mixture of emollient esters with cosmetic applications. Proving that Novozym® 435 leads to minimum savings of 10% with respect to the cheapest immobilized derivative, biocatalyst cost does not appear to be the major contribution to the economics of the processes under study, due to their great capacity to be recovered and reused. At laboratory scale, the biggest economic investment is caused by substrates, which can be massively reduced at industrial scale by using bulk reagents. In such case, energy cost may be the major contribution to the process economy. This work proposes an optimized process ready to be scaled-up in order to accurately determine the energetic requirements of the possible industrial enzymatic synthesis. |
Autor/es principal/es: | Serrano-Arnaldos, A. Montiel, M.C. Ortega-Requena, S. Máximo, F. Bastida, J. |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Ingeniería Química |
Versión del editor: | https://link.springer.com/article/10.1007/s00449-019-02243-1 |
URI: | http://hdl.handle.net/10201/138280 |
DOI: | https://doi.org/10.1007/s00449-019-02243-1 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 26 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
Descripción: | ©<2020>. This manuscript version is made available under the CC-BY-NC-ND license http://creativecommons.org/licenses/ccby-nc-nd/4.0/ This document is the Accepted version of a Published Work that appeared in final form in [Bioprocess and Biosystems Engineering]. To access the final edited and published work see [https://doi.org/ 10.1007/s00449-019-02243-1] |
Aparece en las colecciones: | Artículos: Ingeniería Química |
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Fichero | Descripción | Tamaño | Formato | |
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BBE_2020.pdf | 1,22 MB | Adobe PDF | Visualizar/Abrir |
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