Por favor, use este identificador para citar o enlazar este ítem: https://doi.org/ 10.3390/app13106177

Título: Green Production of a High-Value Branched-Chain Diester: Optimization Based on Operating Conditions and Economic and Sustainability Criteria
Fecha de publicación: 18-may-2023
Editorial: MDPI
Cita bibliográfica: Applied Sciences 2023, 13, 6177
ISSN: Electrónico: 2076-3417
Materias relacionadas: CDU::5 - Ciencias puras y naturales::54 - Química
Palabras clave: Candida antarctica lipase
Rhizomucor miehei lipase
Neopentyl glycol dilaurate
Economic assessment
Green metrics
Resumen: Featured Application: In the last years, consumers’ and administrations’ demand for more sustainable products and processes has been increasing. This work develops a new sustainable way to obtain a branched ester for cosmetic applications (neopentylglycol dilaurate) and demonstrates that this new production route can be economically competitive. Branched-chain esters (BCEs) have found a large number of applications in cosmetics. Among them, neopentyl glycol dilaurate (NPGDL) stands out as an emollient, emulsifier, and skin-conditioning agent. This work presents the synthesis of NPGDL in a solvent-free medium using the two most common immobilized lipases: Novozym® 40086 (Rml) and Novozym® 435 (CalB). Results proved that the former biocatalyst has lower activity and certain temperature deactivation, although conversions ≥ 90% were obtained at 60 °C and 7.5% of catalyst. On the other hand, optimal reaction conditions for Novozym® 435 are 3.75% w/w of the immobilized derivative at 80 °C. Under optimal conditions, the process productivities were 0.105 and 0.169 kg NPGDL/L h, respectively. In order to select the best conditions for NPGDL production, studies on the reuse of the derivative and cost estimation have been performed. Economic study shows that biocatalytic processes can be competitive when lipases are reused for five cycles, yielding biocatalyst productivities of 56 and 122 kg NPGDL/kg biocatalyst using Novozym® 40086 and Novozym® 435, respectively. The final choice will be based on both economic and sustainability criteria. Green metric values using both biocatalysts are similar but the product obtained using Novozym® 40086 is 20% cheaper, making this alternative the best option.
Autor/es principal/es: Montiel, C.
Gimeno-Martos, S.
Ortega-Requena, S.
Serrano-Arnaldos, M.
Máximo, F.
Bastida, J.
Facultad/Departamentos/Servicios: Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Ingeniería Química
Versión del editor: https://www.mdpi.com/2076-3417/13/10/6177
URI: http://hdl.handle.net/10201/138266
DOI: https://doi.org/ 10.3390/app13106177
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 12
Derechos: info:eu-repo/semantics/openAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Descripción: ©<2023>. This manuscript version is made available under the CC-BY license http://creativecommons.org/licenses/by/4.0/ This document is the Published version of a Published Work that appeared in final form in [Applied Sciences]. To access the final edited and published work see [https://doi.org/ 10.3390/app13106177]
Aparece en las colecciones:Artículos: Ingeniería Química

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