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10.1007/s00784-018-2570-3
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Título: | Salivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren's syndrome: a pilot study |
Fecha de publicación: | mar-2019 |
Cita bibliográfica: | Clinical Oral Investigations |
ISSN: | 1432-6981 1436-3771 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Adenosine deaminase Adiponectin Biomarker Clinical signs Saliva Xerostomia |
Resumen: | Abstract Objectives: To evaluate salivary adiponectin and adenosine deaminase (ADA) in women suffering from Sjögren's syndrome (SS). Methods: Salivary adiponectin and ADA were measured in patients with SS (n = 17) and compared to their values in healthy controls (n = 13) and patients suffering from drug-induced xerostomia (non-SS sicca group; n = 19). A clinical history was made for each patient, patients were examined clinically, and xerostomia inventory (XI) was performed. Results: Salivary adiponectin corrected by total protein was higher in patients with SS than in healthy individuals (P < 0.05) or patients with non-SS sicca (P < 0.01) and correlated with XI (r = 0.555; P < 0.05). Salivary ADA was higher in patients with SS and non-SS sicca compared to controls (P < 0.05 in both cases). Conclusion: The results of the present study indicate that adiponectin and ADA are increased in the saliva of patients with SS. Clinical relevance: Salivary adiponectin corrected by total protein can be a potential biomarker of SS. Trial registration: NCT03156569. |
Autor/es principal/es: | López Jornet, María Pía Tvarijonaviciute, Asta Zamora, Carmen Martinez Subiela, Silvia Tecles, Fernando Pina, Francisca |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU |
URI: | http://hdl.handle.net/10201/138135 |
DOI: | 10.1007/s00784-018-2570-3 |
Tipo de documento: | info:eu-repo/semantics/article |
Derechos: | info:eu-repo/semantics/embargoedAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
Aparece en las colecciones: | Artículos: Dermatología, Estomatología, Radiología y Medicina Física |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Salivary adiponectin.pdf | 510,39 kB | Adobe PDF | Visualizar/Abrir Solicitar una copia |
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