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Título: | A meta-analysis of gut microbiota in children with autism |
Fecha de publicación: | 2021 |
Editorial: | Springer |
Cita bibliográfica: | Journal of Autism and Developmental Disorders, 52, 2022, 1374–1387 |
ISSN: | 1573-3432 |
Palabras clave: | Autism spectrum disorders (ASD) Gut microbiota Microbiota-gut-brain axis Systematic review Metaanalysis |
Resumen: | Previous studies have reported dysbiosis in the gut microbiota (GM) of children with autism spectrum disorders (ASD), which may be a determining factor on child development through the microbiota-gut-brain axis. However, it is not clear if there is a specific group of dysbiotic bacteria in ASD. The aim of this study was to carry out a meta-analysis on the studies that analyze GM in children with ASD. 18 studies fulfilled our selection criteria. Our results showed a lower relative abundance of Streptococcus (SMD+ = − 0.999; 95% CI − 1.549, − 0.449) and Bifidobacterium genera (SMD+ = − 0.513; 95% CI − 0.953, − 0.073) in children with ASD. Overall, the Bifidobacterium genera is involved. However, differences found between studies are attributed to factors such as reporting bias. |
Autor/es principal/es: | Andreo Martínez, Pedro Rubio Aparicio, María Sánchez Meca, Julio Veas, Alejandro Martínez González, Agustín Ernesto |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Química Agrícola, Geología y Edafología |
Versión del editor: | https://link.springer.com/article/10.1007/s10803-021-05002-y |
URI: | http://hdl.handle.net/10201/137879 |
DOI: | https://doi.org/10.1007/s10803-021-05002-y |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 14 |
Derechos: | info:eu-repo/semantics/embargoedAccess |
Descripción: | ©2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Published, version of a Published Work that appeared in final form in Journal of Autism and Developmental Disorders. To access the final edited and published work see https://doi.org/10.1007/s10803-021-05002-y |
Aparece en las colecciones: | Artículos: Química Agrícola, Geología y Edafología |
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Fichero | Descripción | Tamaño | Formato | |
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A Meta‑analysis of Gut Microbiota in Children with Autism.pdf | 996,22 kB | Adobe PDF | Visualizar/Abrir Solicitar una copia |
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