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10.3390/biology10050392
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Título: | Proteomics-Based Identification of Salivary Changes in Patients with Burning Mouth Syndrome |
Fecha de publicación: | 1-may-2021 |
Editorial: | MDPI |
Cita bibliográfica: | Biology 2021, 10, 392 |
ISSN: | Electronic: 2079-7737 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas |
Palabras clave: | Burning mouth syndrome Saliva Proteomics |
Resumen: | Burning mouth syndrome (BMS) is a chronic oral condition characterized by an intraoral burning sensation, taste alterations, and dry mouth sensations. The disease affects 0.7–15% of the general population, being most common in post-menopausal women. Although BMS is related to anxiety and/or depression and sleep disturbances, its etiology as well as its diagnosis remain unclear. Therefore, the present study aimed to contribute to the knowledge about this syndrome and to look for objective diagnostic tools. Therefore, whole saliva proteomes of patients suffering from BMS were compared to those of healthy persons. The results of this study manifest alterations in salivary proteins related to stress, immune system, and inflammation and, therefore, suggest implication of these pathways in BMS development. Moreover, biomarkers related to stress, immune system, and inflammation, such as salivary amyloid A, immunoglobulins, or leukocyte elastase inhibitors, among others, could contribute to BMC management, although further research is needed to confirm these suppositions. |
Autor/es principal/es: | Castillo-Felipe, candela Franco-Martínez, Lorena Tvarijonaviciute, Asta Lopez Jornet, Pia Lamy, Elsa |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Dermatología, Estomatología, Radiología y Medicina Física |
Versión del editor: | https://www.mdpi.com/2079-7737/10/5/392 |
URI: | http://hdl.handle.net/10201/137747 |
DOI: | 10.3390/biology10050392 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 13 |
Derechos: | info:eu-repo/semantics/openAccess Atribución 4.0 Internacional |
Descripción: | ©2021. The authors. This document is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by /4.0/ This document is the published version of a published work that appeared in final form in Biology |
Aparece en las colecciones: | Artículos: Dermatología, Estomatología, Radiología y Medicina Física |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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burning-proteinoc.pdf | 1,6 MB | Adobe PDF | Visualizar/Abrir |
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