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Título: | Importance and Antimicrobial Resistance of Mycoplasma bovis in Clinical Respiratory Disease in Feedlot Calves |
Fecha de publicación: | 20-may-2021 |
Editorial: | MDPI |
Cita bibliográfica: | Animals 2021, 11, 1470 |
ISSN: | 2076-2615 |
Palabras clave: | Mycoplasma bovis Pneumonia Antimicrobial resistance Feedlot calves Minimum inhibitory concentration |
Resumen: | Bovine respiratory disease (BRD) is an important viral and/or bacterial disease that mainly affects feedlot calves. The involvement of Mycoplasma bovis in BRD can lead to chronic pneumonia poorly responsive to antimicrobial treatment. Caseonecrotic bronchopneumonia is a pulmonary lesion typically associated with M. bovis. In Spain, M. bovis is widely distributed in the feedlots and circulating isolates are resistant to most antimicrobials in vitro. However, the role of this species in clinical respiratory disease of feedlot calves remains unknown. Furthermore, available data are relative to a fixed panel of antimicrobials commonly used to treat BRD, but not to the specific set of antimicrobials that have been used for treating each animal. This study examined 23 feedlot calves raised in southeast Spain (2016–2019) with clinical signs of respiratory disease unresponsive to treatment. The presence of M. bovis was investigated through bacteriology (culture and subsequent PCR), histopathology and immunohistochemistry. The pathogen was found in 86.9% (20/23) of the calves, mainly in the lungs (78.26%; 18/23). Immunohistochemistry revealed M. bovis antigens in 73.9% (17/23) of the calves in which caseonecrotic bronchopneumonia was the most frequent lesion (16/17). Minimum inhibitory concentration assays confirmed the resistance of a selection of 12 isolates to most of the antimicrobials specifically used for treating the animals in vivo. These results stress the importance of M. bovis in the BRD affecting feedlot calves in Spain |
Autor/es principal/es: | García Galán, Ana Seva, Juan Gómez Martín, Ángel Ortega, Joaquín Rodríguez, Francisco García Muñoz, Angel Fé Rodríguez, Christian de la |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Facultades de la UMU::Facultad de Veterinaria Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Sanidad Animal |
URI: | http://hdl.handle.net/10201/136866 |
DOI: | https://doi.org/ 10.3390/ani11051470 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 14 |
Derechos: | info:eu-repo/semantics/openAccess Atribución 4.0 Internacional |
Descripción: | ©2021. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Published, version of a Published Work that appeared in final form in Animals. To access the final edited and published work see https://doi.org/ 10.3390/ani11051470 |
Aparece en las colecciones: | Artículos: Sanidad Animal |
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