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https://doi.org/10.14670/HH-18-602
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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Virkkunen, Sirke | - |
dc.contributor.author | Willberg, Jaana | - |
dc.contributor.author | Haglund, Caj | - |
dc.contributor.author | Sund, Malin | - |
dc.contributor.author | Sorsa, Timo | - |
dc.contributor.author | Hagström, Jaana | - |
dc.date.accessioned | 2023-09-07T10:29:35Z | - |
dc.date.available | 2023-09-07T10:29:35Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Histology and Histopathology Vol. 38, nº8 (2023) | es |
dc.identifier.issn | 0213-3911 | - |
dc.identifier.issn | 1699-5848 | - |
dc.identifier.uri | http://hdl.handle.net/10201/133730 | - |
dc.description.abstract | Aim. Our aim was to investigate how bacterial lipopolysaccharide (LPS) is immunoexpressed in periapical lesions. By surprise we detected Rushton bodies (RBs) whose origin has been debatable to be positive for LPS. Methodology. Samples of radicular cysts (N=70) were stained in order to identify variations in LPS immunoexpression indicating bacterial background. For immunostaining, we used an anti-LPS antibody from Escherichia coli, and for visualization Horse Radish Peroxidase labeled polymer as the secondary antibody. Results. RBs showed positivity for LPS in radicular cysts. After collection of radicular cyst samples (70 in total), we noted that all RBs (N=25) histologically detected in tissue samples were positive for LPS. Furthermore, calcification in the cyst capsule showed immunopositivity. Conclusion. We demonstrate for the first time that LPS is present in RBs, indicating that host response to bacteria might be the initial cause of the formation of these hyaline bodies in the cyst epithelium and cyst capsule calcifications. | es |
dc.format | application/pdf | es |
dc.format.extent | 4 | es |
dc.language | eng | es |
dc.publisher | Universidad de Murcia, Departamento de Biologia Celular e Histiologia | es |
dc.relation | Sin financiación externa a la Universidad | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Lipopolysaccharide | es |
dc.subject | Periapical lesions | es |
dc.subject | Radicular cyst | es |
dc.subject | Rushton bodies | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología | es |
dc.title | Ex vivo detection of lipopolysaccharide immunopositivity in Rushton bodies | es |
dc.type | info:eu-repo/semantics/article | es |
dc.identifier.doi | https://doi.org/10.14670/HH-18-602 | - |
Aparece en las colecciones: | Vol.38, nº8 (2023) |
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