Por favor, use este identificador para citar o enlazar este ítem:
https://doi.org/10.14670/HH-18-457
Twittear
Registro completo de metadatos
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Chen, Kuang Qi | - |
dc.contributor.author | Wei, Bang Hong | - |
dc.contributor.author | Hao, Shuang Li | - |
dc.contributor.author | Yang, Wan Xi | - |
dc.date.accessioned | 2023-02-23T11:42:20Z | - |
dc.date.available | 2023-02-23T11:42:20Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Histology and Histopathology Vol. 37, nº7 (2022) | es |
dc.identifier.issn | 0213-3911 | - |
dc.identifier.issn | 1699-5848 | - |
dc.identifier.uri | http://hdl.handle.net/10201/128692 | - |
dc.description.abstract | The PI3K/AKT signaling pathway is one of the most crucial regulatory mechanisms in animal cells, which can mainly regulate proliferation, survival and anti-apoptosis in cell lines. In the seminiferous epithelium, most studies were concentrated on the role of PI3K/AKT signaling in immature Sertoli cells (SCs) and spermatogonia stem cells (SSCs). PI3K/AKT signaling can facilitate the proliferation and antiapoptosis of immature Sertoli cells and spermatogenic cells. Besides, in mature Sertoli cells, this pathway can disintegrate the structure of the blood-testis barrier (BTB) via regulatory protein synthesis and the cytoskeleton of Sertoli cells. All of these effects can directly and indirectly maintain and promote spermatogenesis in male testis. | es |
dc.format | application/pdf | es |
dc.format.extent | 16 | es |
dc.language | eng | es |
dc.publisher | Universidad de Murcia, Departamento de Biologia Celular e Histiologia | es |
dc.relation | Sin financiación externa a la Universidad | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | PI3K/AKT signaling | es |
dc.subject | Sertoli cell | es |
dc.subject | Spermatogonia stem cell | es |
dc.subject | Blood testis barrier | es |
dc.subject | Spermatogenesis | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología | es |
dc.title | The PI3K/AKT signaling pathway: How does it regulate development of Sertoli cells and spermatogenic cells? | es |
dc.type | info:eu-repo/semantics/article | es |
dc.identifier.doi | https://doi.org/10.14670/HH-18-457 | - |
Aparece en las colecciones: | Vol.37, nº7 (2022) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Chen-37-621-636-2022.pdf | 3,94 MB | Adobe PDF | Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons