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https://doi.org/10.14670/HH-18-307
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| Título: | Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish |
| Fecha de publicación: | 2021 |
| Editorial: | Universidad de Murcia, Departamento de Biologia Celular e Histiologia |
| Cita bibliográfica: | Histology and Histopathology Vol. 36, nº7 (2021) |
| ISSN: | 0213-3911 1699-5848 |
| Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
| Palabras clave: | Induced pluripotent stem cells Retinal organoids Inherited retinal dystrophy Gene editing Disease modeling |
| Resumen: | Induced pluripotent stem cells (iPSCs), reprogrammed from human somatic cells, hold the capacity to differentiate into most human body cells. iPSCs can be differentiated into retinal organoids, a three-dimensional structured retina containing various retinal cells. Patient-specific retinal organoids provide a powerful disease model to recapitulate the disease to study the pathogenesis of inherited retinal dystrophies, to screen or discover new drugs, and most importantly to supply an unlimited cell source for retinal regeneration |
| Autor/es principal/es: | Zhang, Xiao-Hui Jin, Zi-Bing |
| URI: | http://hdl.handle.net/10201/127527 |
| DOI: | https://doi.org/10.14670/HH-18-307 |
| Tipo de documento: | info:eu-repo/semantics/article |
| Número páginas / Extensión: | 6 |
| Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
| Aparece en las colecciones: | Vol.36, nº7 (2021) |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| Zhang-36-705-710-2021.pdf | 2,53 MB | Adobe PDF |  Visualizar/Abrir |
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