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https://doi.org/10.14670/HH-18-148
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Título: | Advances in understanding mechanisms of long-term sperm storage-the soft-shelled turtle model |
Fecha de publicación: | 2020 |
Editorial: | Universidad de Murcia, Departamento de Biologia Celular e Histiologia |
Cita bibliográfica: | Histology and Histopathology Vol. 35, nº 1 (2020) |
ISSN: | 0213-3911 1699-5848 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
Palabras clave: | Long-term sperm storage Exosomes Androgen receptors Autophagy Soft-shelled turtle |
Resumen: | Long-term sperm storage is a special reproductive strategy, which can extend the time window between mating and fertilization in some animal species. Spermatozoa of the soft-shelled turtle, Pelodiscus sinensis, can be stored in the epididymis and oviduct for at least six months and one year, respectively. How spermatozoa can be stored in vivo for such a prolonged period is yet to be explained. We analyze the mechanisms that contribute to long-term sperm storage in P. sinensis, and compare them with other species from three different perspectives: the spermatozoon itself, the storage microenvironment and the interaction between the spermatozoon and microenvironment. Characteristics of soft-shelled turtle spermatozoa itself, such as the huge cytoplasmic droplet with its content of several large lipid droplets (LDs) and onion-like mitochondira, facilitate long-term sperm storage. The microenvironment of reproductive tract, involving in the secretions, structural barriers, exosomes, androgen receptors, Toll-like receptors and survival factor Bcl-2, are important for the maintenance of spermatozoa long-term storage. Sperm heads are always embedded among the oviductal cilia and even intercalate into the apical hollowness of the ciliated cells, indicating that the ciliated cells support the stored spermatozoa. RNA seq is firstly used to detect the molecular mechanism of sperm storage, which shows that autophagy, apoptosis and immune take part in the long-term sperm storage in this species |
Autor/es principal/es: | Chen, Hong Liu, Tengfei Holt, William V. Yang, Ping Zhang, Linli Zhang, Li Han, Xiangkun Bian, Xunguang Chen, Qiusheng |
URI: | http://hdl.handle.net/10201/124986 |
DOI: | https://doi.org/10.14670/HH-18-148 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 23 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
Aparece en las colecciones: | Vol.35, nº1 (2020) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Chen-35-1-23-2020.pdf | 19,54 MB | Adobe PDF | Visualizar/Abrir |
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